merck millipore,默克密理博,MABE421,Anti-Lymphoid-specific helicase (SMARCA6) Antibody, clone 2G7.1

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Merck Millipore 默克密理愽

品种反应性	主要应用	宿主	格式	抗体类型
H	IHC, WB	M	Purified	Monoclonal Antibody

描述
产品目录编号	MABE421
描述	Anti-Lymphoid-specific helicase (SMARCA6) Antibody, clone 2G7.1
Alternate Names	SWI/SNF2-related matrix-associated actin-dependent regulator of chromatin subfamily A member 6 Lymphoid-specific helicase Proliferation-associated SNF2-like protein
背景信息	A member of the SNF2 family of chromatin remodeling proteins, Lymphoid-specific helicase (HELLS, also known as Lsh) assumes various roles in normal development, survival, de novo or maintenance DNA methylation, gene silencing, and heterochromatin formation and organization. It is shown to serve as cancer progression marker in conjunction with CEP55 and FOXM1 for the detection of head and neck squamous cell carcinoma (HNSCC). It is also reported that expression of Lsh is crucial for meiotic progression in mouse spermatocytes. Lsh is shown to directly associate with the 5' DMR of the Cdkn1c promoter, and thereby regulate its gene expression. Additionally, Lsh is reported as a regulator of repressive chromatin at retrotransposons, and is demonstrated to mediate the silencing of stem cell-specific genes such as Oct4.

产品信息
格式	Purified
演示	Purified mouse monoclonal IgG1κ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

应用
应用	This Anti-Lymphoid-specific helicase (SMARCA6) Antibody, clone 2G7.1 is validated for use in western blotting & IHC for the detection of Lymphoid-specific helicase (SMARCA6).
主要应用	Immunohistochemistry Western Blotting
应用说明	Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected Lymphoid-specific helicase (SMARCA6) in human placenta tissue.

生物信息
免疫原品种	GST-tagged recombinant protein corresponding to human Lymphoid-specific helicase (SMARCA6).
克隆	2G7.1
浓缩	Please refer to the Certificate of Analysis for the lot-specific concentration.
宿主	Mouse
同种型	IgG1κ
品种反应性	Human
抗体类型	Monoclonal Antibody
Entrez基因编号	NP_060533
基因符号	SMARCA6 HELLS PASG
纯化方法	Protein G purified
UniProt编号	Q9NRZ9

产品使用声明
质量保证	Evaluated by Western Blotting in human thymus tissue lysate. Western Blotting Analysis: 1.0 µg/mL of this antibody detected Lymphoid-specific helicase (SMARCA6) in 10 µg of human thymus tissue lysate.
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Stable for 1 year at 2-8°C from date of receipt.

包装信息
数量	100 µg

merck millipore,默克密理博,MABE421,Anti-Lymphoid-specific helicase (SMARCA6) Antibody, clone 2G7.1

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