- 当前位置：首页 > >Merck Millipore > 生命科学研究
- 生命科学研究
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 H IHC, FC, WB M Purified Monoclonal Antibody 描述 产品目录编号 CBL511 品牌系列 Chemicon®
商名 - Chemicon
描述 Anti-CD55 Antibody, clone BRIC 216 Alternate Names - DAF
产品信息 格式 Purified 演示 The immunoglobulin was purified from cell culture supernatant by affinity chromatography using protein G and is presented in 1 M Tris-buffered saline, pH 7.5, containing no preservatives. The antibody has been sterile-filtered. 应用 应用 Anti-CD55 Antibody, clone BRIC 216 is an antibody against CD55 for use in FC, IP, WB, IH, IH(P). 主要应用 - Immunohistochemistry
- Flow Cytometry
- Western Blotting
应用说明 Western blot: Non-reduced erythrocyte membrane prep; antigen is sialidase and trypsin resistant, pronase, chymotrypsin and AET sensitive
Flow Cytometry
Immunohistochemistry: Frozen and formalin-fixed paraffin-embedded sections. Protease antigen retreival is recommended.
Immunoprecipitation
Inhibition studies
Optimal working dilutions must be determined by the end user.生物信息 免疫原品种 Human fibroblast cell line 克隆 BRIC 216 宿主 Mouse 特异性 This antibody recognizes the CD55 antigen a 70 kDa glycoprotein also known as Decay Accelerating Factor (DAF). The antigen is present on erthrocytes and other circulating blood cells and also on cells in non-haemopoietic tissue particularly epithelium and endothelium. It is found specifically at the placental fetal-maternal interface. 同种型 IgG1 品种反应性 Human 抗体类型 Monoclonal Antibody Entrez基因编号 - NM_000574.2
Entrez基因汇总 This gene encodes a protein involved in the regulation of the complement cascade. The encoded glycoprotein is also known as the decay-accelerating factor (DAF); binding of DAF to complement proteins accelerates their decay, disrupting the cascade and preventing damage to host cells. Antigens present on the DAF glycoprotein constitute the Cromer blood group system (CROM). Two alternatively spliced transcripts encoding different proteins have been identified. The predominant transcript encodes a membrane-bound protein expressed on cells exposed to plasma component proteins but an alternatively spliced transcript produces a soluble protein present at much lower levels. Additional, alternatively spliced transcript variants have been described, but their biological validity has not been determined. 基因符号 - DAF
- CD55
- CR
- TC
纯化方法 Protein G purfied UniProt编号 - P08174
UniProt汇总 FUNCTION: SwissProt: P08174 # Also acts as the receptor for echovirus 7 and related viruses (echoviruses 13, 21, 29 and 33).
SIZE: 381 amino acids; 41400 Da
SUBUNIT: Monomer (major form) and non-disulfide-linked, covalent homodimer (minor form).
SUBCELLULAR LOCATION: Isoform 2: Cell membrane; Lipid-anchor, GPI- anchor.
TISSUE SPECIFICITY: Expressed on the plasma membranes of all cell types that are in intimate contact with plasma complement proteins. It is also found on the surfaces of epithelial cells lining extracellular compartments, and variants of the molecule are present in body fluids and in extracellular matrix.
DOMAIN: SwissProt: P08174 The first Sushi domain (SCR1) is not necessary for function. SCR2 and SCR4 provide the proper conformation for the active site on SCR3 (By similarity).
PTM: The Ser/Thr-rich domain is heavily O-glycosylated.
SIMILARITY: Belongs to the receptors of complement activation (RCA) family. & Contains 4 Sushi (CCP/SCR) domains.产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Aliquot antibody into small volumes and store at -20°C for up to 12 months from the date of receipt. 包装信息 数量 100 µg
上一件merck millipore产品：merck millipore,默克密理博,ABE632,Anti-POLR1C Antibody
下一件merck millipore产品：merck millipore,默克密理博,PC730,Anti-IDE, N-Terminal (97-273) Rabbit pAb
相关产品
merck millipore,默克密理博,CBL1337,Anti-PECAM-1 Antibody, clone 390
merck millipore,默克密理博,14-779M,MKP5, active
merck millipore,默克密理博,GF309,NT-4 Protein, Human Recombinant Animal Free
merck millipore,默克密理博,71431,Origami™ 2 Competent Cell Set* - Novagen
merck millipore,默克密理博,ABE632,Anti-POLR1C Antibody
merck millipore,默克密理博,PC730,Anti-IDE, N-Terminal (97-273) Rabbit pAb
merck millipore,默克密理博,04-430,Anti-AIF Antibody, rabbit monoclonal
merck millipore,默克密理博,17-646,ChIPAb+ HP1γ - ChIP Validated Antibody and Primer Set
merck millipore,默克密理博,SF-1692,PIKFYVE; Human, Cyanine 5 RNA Detection Probe,SmartFlare
merck millipore,默克密理博,AB1528SP,Anti-Nerve Growth Factor-β Antibody