merck millipore,默克密理愽
  • merck millipore,默克密理博,CBL2117,Anti-Interleukin-6 Antibody, clone B-E8

  • merck millipore,默克密理博,CBL2117,Anti-Interleukin-6 Antibody, clone B-E8

    产品名称：Anti-Interleukin-6 Antibody, clone B-E8
    产品型号：CBL2117
    Detect Interleukin-6 using this Anti-Interleukin-6 Antibody, clone B-E8 validated for use in ELISA, FC, IH, NEUT.

    merck millipore,默克密理博,CBL2117,Anti-Interleukin-6 Antibody, clone B-E8

  • 产品介绍
  • merck millipore,默克密理博,CBL2117,Anti-Interleukin-6 Antibody, clone B-E8

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    HIHC, ELISA, FCMPurifiedMonoclonal Antibody
    描述
    产品目录编号 CBL2117
    Replaces 04-1095
    品牌系列 Chemicon®
    商名
    • Chemicon
    描述 Anti-Interleukin-6 Antibody, clone B-E8
    Alternate Names
    • Interferon beta-2
    • IL-6
    • B-cell stimulatory factor 2
    产品信息
    格式 Purified
    演示 The monoclonal is purified from tissue culture supernatant by ion exchange chromatography and is presented as a liquid in phosphate buffered saline, pH 7.2, containing 0.09% sodium azide.
    应用
    应用 Detect Interleukin-6 using this Anti-Interleukin-6 Antibody, clone B-E8 validated for use in ELISA, FC, IH, NEUT.
    主要应用
    • Immunohistochemistry
    • ELISA
    • Flow Cytometry
    应用说明 Blocks Interleukin-6 induced proliferation on B9 cells: 20pg of antibody neutralizes the activity of 1U of IL-6. It is recommended that the sodium azide is removed from the antibody prior to use in this application.

    Immunohistochemistry on frozen sections

    Optimal working dilutions must be determined by the end user.
    生物信息
    免疫原品种 Recombinant human IL-6.
    克隆 B-E8
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Mouse
    特异性 Recognizes natural and recombinant forms of human Interleukin-6 with an affinity of 0.5 nM. Inhibits IL-6 binding to its receptors and blocks Interleukin-6 induced proliferation on B9 cells.
    同种型 IgG1
    品种反应性 Human
    抗体类型 Monoclonal Antibody
    Entrez基因编号
    • NM_000600.2
    基因符号
    • IFNB2
    • IL6
    • HSF
    • BSF-2
    • HGF
    • IL-6
    • BSF2
    • CDF
    非反应性品种
    • Mouse
    UniProt编号
    • P05231
    UniProt汇总 FUNCTION: SwissProt: P05231 # IL-6 is a cytokine with a wide variety of biological functions: it plays an essential role in the final differentiation of B-cells into Ig-secreting cells, it induces myeloma and plasmacytoma growth, it induces nerve cells differentiation, in hepatocytes it induces acute phase reactants.
    SIZE: 212 amino acids; 23718 Da
    SUBCELLULAR LOCATION: Secreted.
    PTM: N- and O-glycosylated.
    DISEASE: SwissProt: P05231 # Genetic variations in IL6 are associated with susceptibility to systemic juvenile rheumatoid arthritis [MIM:604302]. Systemic juvenile rheumatoid arthritis is juvenile chronic arthritis associated with severe, debilitating, extraarticular features, and occasionally fatal complications. Despite medical treatment, many children still experience early joint destruction, necessitating surgical replacement. & At least 1 polymorphism in the IL6 gene renders HIV- infected men susceptible to Kaposi sarcoma [MIM:148000]. Kaposi sarcoma is a sarcoma of spindle cells mixed with angiomatous tissue. A relatively rare malignant skin tumor that results in multifocal purplish coloured papules or plaques that eventually form nodules. Most commonly seen in patients who suffer from AIDS.
    SIMILARITY: SwissProt: P05231 ## Belongs to the IL-6 superfamily.
    产品使用声明
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Store at 2-8°C for up to 12 months from date of receipt. For long term storage aliquot antibody into small volumes and store at -20°C. Avoid repeated freeze-thaw cycles.
    包装信息
    数量 100 µg

    merck millipore,默克密理博,CBL2117,Anti-Interleukin-6 Antibody, clone B-E8

上一件merck millipore产品：merck millipore,默克密理博,ABE1374,Anti-EGR-2 Antibody
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