merck millipore,默克密理愽
  • merck millipore,默克密理博,CBL150F,Anti-CD3 Antibody, clone UCHT1, FITC conjugated

  • merck millipore,默克密理博,CBL150F,Anti-CD3 Antibody, clone UCHT1, FITC conjugated

    产品名称：Anti-CD3 Antibody, clone UCHT1, FITC conjugated
    产品型号：CBL150F
    Anti-CD3 Antibody, clone UCHT1, FITC conjugated is an antibody against CD3 for use in FC, IH.

    merck millipore,默克密理博,CBL150F,Anti-CD3 Antibody, clone UCHT1, FITC conjugated

  • 产品介绍
  • merck millipore,默克密理博,CBL150F,Anti-CD3 Antibody, clone UCHT1, FITC conjugated

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    HIHC, FCMFITCMonoclonal Antibody
    描述
    产品目录编号 CBL150F
    Replaces CBL126F
    品牌系列 Chemicon®
    商名
    • Chemicon
    描述 Anti-CD3 Antibody, clone UCHT1, FITC conjugated
    Alternate Names
    • TCR
    产品信息
    格式 FITC
    演示 The conjugate is supplied as a 100 test/1 mL vial in phosphate buffered saline containing 10mM sodium azide and 1mg/ml bovine serum albumin. For flow cytometry we recommend using 10μL of conjugate per test.
    应用
    应用 Anti-CD3 Antibody, clone UCHT1, FITC conjugated is an antibody against CD3 for use in FC, IH.
    主要应用
    • Immunohistochemistry
    • Flow Cytometry
    应用说明 Flow Cytometry

    Identification of CD3 positive T lymphocytes by indirect immunofluorescence staining

    Identification of normal and malignant T lymphocytes in frozen tissue sections

    Immunoprecipitation of the CD3 antigen

    Mitogenic stimulation of T lymphocytes with or without the presence of IL-2

    Leukaemia and lymphoma phenotyping

    Optimal dilutions must be determined by end user.
    生物信息
    免疫原品种 Purified human T cells
    克隆 UCHT1
    宿主 Mouse
    特异性 This antibody recognizes 22/26/30 kDa molecular weight lymphocyte surface molecules associated with the T cell antigen receptor complex. It reacts with the majority of peripheral blood T lymphocytes, a major proportion of thymocytes, the majority of T cell chronic lymphocytic leukaemia cells, Sézary leukaemias and approximately 70% of acute lymphoblastic leukaemias of T cell origin.
    Antigen distribution:
    T cells 100%
    Peripheral Blood lymphocytes 75 + 7%
    Thymocytes 68 + 5%
    Granulocytes < 1%
    Monocytes < 1%
    B cells (E-) < 1%
    NK cells (CD16+) < 1%
    KNOWN SPECIES CROSS REACTIVITY: Negative with rhesus monkey peripheral blood leucocytes in flow cytometry
    FUSION PARTNER: P3 x 63 Ag8.653 myeloma cell line
    同种型 IgG1
    品种反应性 Human
    抗体类型 Monoclonal Antibody
    Entrez基因编号
    • NM_000733.2
    Entrez基因汇总 The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women.
    基因符号
    • TCRE
    • CD3E
    • T3E
    非反应性品种
    • Monkey
    UniProt编号
    • P07766
    UniProt汇总 FUNCTION: SwissProt: P07766 # The CD3 complex mediates signal transduction.
    SIZE: 207 amino acids; 23147 Da
    SUBUNIT: The TCR/CD3 complex of T-lymphocytes consists of either a TCR alpha/beta or TCR gamma/delta heterodimer coexpressed at the cell surface with the invariant subunits of CD3 labeled gamma, delta, epsilon, zeta, and eta.
    SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.
    SIMILARITY: SwissProt: P07766 ## Contains 1 Ig-like (immunoglobulin-like) domain. & Contains 1 ITAM domain.
    产品使用声明
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Store at +4°C protected from light. DO NOT FREEZE. For long term use and storage aliquot conjugate into small volumes and store at +4°C.
    包装信息
    数量 100 assays

    merck millipore,默克密理博,CBL150F,Anti-CD3 Antibody, clone UCHT1, FITC conjugated

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