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品种反应性 主要应用 宿主 格式 抗体类型 H WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 ABT129 Replaces 04-589 描述 Anti-Calponin-1 Antibody Alternate Names - Basic calponin, Calponin H1, smooth muscle
- Calponin-1
背景信息 Calponin 1 is a 34 kDa protein that is predominantly found in smooth muscle tissue. It is a high-affinity actin-binding protein, but also interacts with tropomyosin, and calmodulin to modulate muscle contraction. When bound to F-actin, it inhibits the activity of the actin-activated myosin ATPase. Calponin 1 is regulated by reversible phosphorylation involving PKC and CAMKII kinases, and type 2A phosphatases. In non-muscle cells, calponin 1 may play a role in cell migration, motility, and proliferation. 产品信息 格式 Affinity Purified 控制 - Human aortic smooth muscle tissue
演示 Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. 应用 应用 This Anti-Calponin-1 Antibody is validated for use in Western Blotting, IHC(P), Immunofluorescence for the detection of Calponin-1. 主要应用 - Western Blotting
应用说明 Immunohistochemistry Analysis: A 1:1,000 dilution from a reprsesentative lot detected Calponin-1 in human seminal vesicle tissue.
Immunofluorescence Analysis: A 1:500 dilution from a representative lot detected Calponin-1 in smooth muscle cells from human seminal vesicle tissue.生物信息 免疫原品种 KLH-conjugated linear peptide corresponding to the C-terminus of human Calponin-1. 表位 C-terminus 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 特异性 This antibody recognizes the C-terminus of Calponin-1. 品种反应性 Human Species Reactivity Note Demonstrated to react with Human. Predicted to react with Bovine, Chimpanzee, and Sheep based on 100% sequence homology. Other homologies: Rat (92% sequence homology) and Mouse (83% sequence homology). 抗体类型 Polyclonal Antibody Entrez基因编号 - NP_001290
基因符号 - CNN1
纯化方法 Affinity purified UniProt编号 - P51911
产品使用声明 质量保证 Evaluated by Western Blot in human aortic smooth muscle tissue.
Western Blot Analysis: 0.1 µg/mL of this antibody detected Calponin-1 in human aortic smooth muscle tissue.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
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