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merck millipore,默克密理博,ABN489,Anti-PEN2 Antibody
产品名称：Anti-PEN2 Antibody
产品型号：ABN489
Anti-PEN2 Antibody is a highly specific rabbit polyclonal antibody, that targets Presenilin enhancer protein 2 & has been tested in western blotting, IHC & Immunofluorescence.
merck millipore,默克密理博,ABN489,Anti-PEN2 Antibody
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 R, M IHC, WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 ABN489 描述 Anti-PEN2 Antibody Alternate Names - PEN2
- Presenilin enhancer protein 2
- Gamma-secretase subunit PEN-2
- PSENEN
- MDS033
背景信息 Gamma-secretase subunit PEN-2 (PEN2) is also known as Presenilin enhancer protein 2 (PSENEN) and catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). PEN2 is an essential component of the gamma-secretase complex and may play an important role in the last step of the maturation process of gamma-secretases, facilitating endoproteolysis of presenilin and gamma-secretase activity. PEN2 is widely expressed, more specifically in leukocytes, lung, liver, placenta, small intestine, skeletal muscle, kidney, spleen thymus, heart and brain. Defects in PEN2 may be the cause of familial acne inversa type 2, a chronic relapsing inflammatory disease of the hair follicles characterized by recurrent draining sinuses, painful skin abscesses, and disfiguring scars. Additionally, PEN2 is suggested to be related to Alzheimer's disease. 产品信息 格式 Affinity Purified 控制 - A-20 cell lysate
演示 Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide. 应用 应用 Anti-PEN2 Antibody is a highly specific rabbit polyclonal antibody, that targets Presenilin enhancer protein 2 & has been tested in western blotting, IHC & Immunofluorescence. 主要应用 - Immunohistochemistry
- Western Blotting
应用说明 Immunohistochemistry Analysis: 2.5 µg/mL from a representative lot detected PEN2 in rat lung tissue.
Immunofluorescence Analysis: 20 µg/mL from a representative lot detected PEN2 in rat lung cells.生物信息 免疫原品种 KLH-conjugated linear peptide corresponding to the N-terminus of human PEN2. 表位 N-terminus 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 特异性 This antibody recognizes the N-terminus of PEN2. 品种反应性 RatMouse 抗体类型 Polyclonal Antibody 基因符号 - PSENEN
纯化方法 Antigen Affinity purified UniProt编号 - Q9NZ42
产品使用声明 质量保证 Evaluated by Western Blotting in A-20 cell lysate.
Western Blotting Analysis: 1 µg/mL of this antibody detected PEN2 in 15 µg of A-20 cell lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
上一件merck millipore产品：merck millipore,默克密理博,480420,NF449 - CAS 389142-38-5 - Calbiochem
下一件merck millipore产品：merck millipore,默克密理博,1590-OP,OmniPur Acrylamide:Bis-acrylamide, 29:1 Premixed Powder - Calbiochem
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