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重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 H ICC, WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 ABC332 描述 Anti-RICK Antibody Alternate Names - PRO34092
- RIP2
- Receptor-interacting serine/threonine-protein kinase 2
- CARD-containing interleukin-1 beta-converting enzyme-associated kinase
- CARD-containing IL-1 beta ICE-kinase
- RIP-like-interacting CLARP kinase
- Receptor-interacting protein 2
- RIP-2
- Tyrosine-protein kinase RIPK2
- CARDIAK
- RICK
- UNQ277
- PRO314
背景信息 Receptor-interacting serine/threonine-protein kinase 2 (RIPK2), also known as CARD-containing interleukin-1 beta-converting enzyme-associated kinase (CARDIAK), RIP-like-interacting CLARP kinase, Receptor-interacting protein 2 (RIP-2), and Tyrosine-protein kinase RIPK2, is a member of the TKL Ser/Thr family. RICK is a serine/threonine/tyrosine kinase that has been shown to play an important role in modulation of innate and adaptive immune responses. Studies have indicated that RICK may play an essential role in immune response, growth control, and apoptosis. It is also suggested to play a role during engagement of the T-cell receptor (TCR) in promoting BCL10 phosphorylation and subsequent NF-kappa-B activation. RICK interacts with members of the TRAF family, CLARP and caspase-1 and is implied to regulate TNF and Fas induced-apoptosis, which is involved in the generation of proinflammatory cytokine IL-1beta. RICK is expressed in heart, brain, placenta, lung, peripheral blood leukocytes, spleen, kidney, testis, prostate, pancreas and lymph node. 产品信息 格式 Affinity Purified 控制 - A431 and K562 cell lysates
演示 Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide. 应用 应用 Anti-RICK Antibody is a highly specific rabbit polyclonal antibody, that targets RICK & has been tested in western blotting & ICC. 主要应用 - Immunocytochemistry
- Western Blotting
应用说明 Immunocytochemistry Anlaysis: 10 µg/mL from a representative lot detected RICK in A431 cells. 生物信息 免疫原品种 KLH-conjugated linear peptide corresponding to the N-terminus of human RICK. 表位 N-terminus 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 特异性 This antibody recognizes the N-terminus of RICK. 品种反应性 Human 抗体类型 Polyclonal Antibody 基因符号 - RIPK2
纯化方法 Antigen Affinity purified UniProt编号 - O43353
产品使用声明 质量保证 Evaluated by Western Blotting in A431 and K562 cell lysates.
Western Blotting Analysis: 1 µg/mL of this antibody detected RICK in 15 µg of A431 and K562 cell lysates.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
上一件merck millipore产品：merck millipore,默克密理博,17-10139,ChIPAb+™ Phospho-Histone H3 (Thr11) - ChIP Validated Antibody and Primer Set
下一件merck millipore产品：merck millipore,默克密理博,480420,NF449 - CAS 389142-38-5 - Calbiochem
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