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品种反应性 主要应用 宿主 抗体类型 H, M, R IHC, WB Rb Polyclonal Antibody 描述 产品目录编号 ABN307 描述 Anti-LGI1 Antibody Alternate Names - EPT
- Leucine-rich
- glioma inactivated 1
- epitempin
背景信息 The leucine-rich, glioma inactivated gene 1 (LGI1) was first identified as tumor suppressor gene for glioma and may play a role in other cancers. LGI1 is a member of a family of highly related proteins containing leucine-rich repeats (LRRs) which are very similar to other transmembrane signaling molecules and receptors. LGI1 serves as a ligand to ADAM22, a metalloprotease localized at the synapse. Mutations in LGI1 account for nearly half of autodominant lateral temporal epilepsy (ADTLE), an epileptic syndrome characterized by focal seizures with predominant auditory symptoms. 产品信息 控制 - Mouse brain tissue lysate
演示 Purified rabbit polyclonal in buffer containing PBS with 0.02% sodium azide. 应用 应用 Detect the LGI1 protein using this Anti-LGI1 validated for use in WB & IHC. 主要应用 - Immunohistochemistry
- Western Blotting
应用说明 Western Blot Analysis: 2 µg/mL from a representative lot detected LGI1 in 10 µg/mL of HEK293 cell lysate.
Immunohistochemistry Analysis: A 1:2,000 dilution from a representative lot detected LGI1 in mouse cerebellum and rat cortex tissues.生物信息 免疫原品种 KLH-conjugated linear peptide corresponding to human LGI1. 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 特异性 This antibody recognizes only Isoform 1. 品种反应性 HumanMouseRat Species Reactivity Note Demonstrated to react with Human, Mouse, and Rat. 抗体类型 Polyclonal Antibody 基因符号 - LGI1
纯化方法 Antigen Affinity purified UniProt编号 - O95970
产品使用声明 质量保证 Evaluated by Western Blot in mouse brain tissue lysate.
Western Blot Analysis: 2 µg/mL of this antibody detected LGI1 in 10 µg/mL of mouse brain tissue lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
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