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  • merck millipore,默克密理博,ABT70,Anti-WASH complex subunit 7 (SWIP) Antibody

  • merck millipore,默克密理博,ABT70,Anti-WASH complex subunit 7 (SWIP) Antibody

    产品名称：Anti-WASH complex subunit 7 (SWIP) Antibody
    产品型号：ABT70
    Detect WASH complex subunit 7 (SWIP) using this Anti-WASH complex subunit 7 (SWIP) Antibody validated for use in IP.

    merck millipore,默克密理博,ABT70,Anti-WASH complex subunit 7 (SWIP) Antibody

  • 产品介绍
  • merck millipore,默克密理博,ABT70,Anti-WASH complex subunit 7 (SWIP) Antibody

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    HIPRbPurifiedPolyclonal Antibody
    描述
    产品目录编号 ABT70
    描述 Anti-WASH complex subunit 7 (SWIP) Antibody
    Alternate Names
    • WASH complex subunit 7
    背景信息 WASH complex subunit 7 (SWIP) is a component of the WASH complex belonging to the WASH S7 family. The WASH complex is localized at early endosomal subdomains involved in the activation and recruitment the ARP 2/3 complex in order to stimulate actin polymerization and tubulin interaction. Through its interaction with FAM21, WASH plays a regulatory role in the retromer-mediated trafficking of vesicles. It is also involved in the tubule fission, components required in endosomal sorting processes as transport intermediates.
    产品信息
    格式 Purified
    控制
    • HeLa immunoprecipitation with rabbit IgG and Anti-WASH complex subunit 7
    演示 Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
    应用
    应用 Detect WASH complex subunit 7 (SWIP) using this Anti-WASH complex subunit 7 (SWIP) Antibody validated for use in IP.
    主要应用
    • Immunoprecipitation
    生物信息
    免疫原品种 GST-tagged recombinant protein corresponding to human WASH complex subunit 7.
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Rabbit
    品种反应性 Human
    Species Reactivity Note Demonstrated to react with human.
    抗体类型 Polyclonal Antibody
    Entrez基因编号
    • NP_056090.1
    基因符号
    • KIAA10331
    纯化方法 Protein G Purified
    UniProt编号
    • Q2M389
    UniProt汇总 FUNCTION: Component of the WASH complex, a complex present at the surface of endosomes that recruits and activates the Arp2/3 complex to induce actin polymerization. The WASH complex plays a key role in the fission of tubules that serve as transport intermediates during endosome sorting By similarity.

    SUBUNIT STRUCTURE: Component of the WASH complex, composed of F-actin-capping protein subunit alpha (CAPZA1, CAPZA2 or CAPZA3), F-actin-capping protein subunit beta (CAPZB), WASH (WASH1, WASH2P, WASH3P, WASH4P, WASH5P or WASH6P), FAM21 (FAM21A, FAM21B or FAM21C), KIAA1033, KIAA0196 and CCDC53.

    SEQUENCE SIMILARITIES: Belongs to the WASHS7 family.

    SEQUENCE CAUTION: The sequence AAI10851.1 differs from that shown. Reason: Contaminating sequence. Potential poly-A sequence.

    The sequence BAA82985.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.
    产品使用声明
    质量保证 Evaluated by Immunoprecipitation/Western Blot Analysis in HeLa immunoprecipitation with rabbit IgG and Anti-WASH complex subunit 7.

    Immunoprecipitation/Western Blot Analysis: 5 µg/mL of this antibody detected WASH complex subunit 7 in 10 µg of HeLa immunoprecipitation with rabbit IgG and Anti-WASH complex subunit 7.
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Stable for 1 year at 2-8°C from date of receipt.
    包装信息
    数量 100 µg

    merck millipore,默克密理博,ABT70,Anti-WASH complex subunit 7 (SWIP) Antibody

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