merck millipore,默克密理博,AB5714,Anti-Hey 1/HRT1 Antibody

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merck millipore,默克密理博,AB5714,Anti-Hey 1/HRT1 Antibody
产品名称：Anti-Hey 1/HRT1 Antibody
产品型号：AB5714
Anti-Hey 1/HRT1 Antibody detects level of Hey 1/HRT1 & has been published & validated for use in WB, IH.

merck millipore,默克密理博,AB5714,Anti-Hey 1/HRT1 Antibody

产品介绍

merck millipore,默克密理博,AB5714,Anti-Hey 1/HRT1 Antibody

重要规格表

品种反应性	主要应用	宿主	格式	抗体类型
M, H	IHC, WB	Rb	Affinity Purified	Polyclonal Antibody

描述
产品目录编号	AB5714
品牌系列	Chemicon®
商名	Chemicon
描述	Anti-Hey 1/HRT1 Antibody

产品信息
格式	Affinity Purified
演示	Precipitated antibody in a solution of 50% saturated ammonium sulfate and PBS containing no preservatives.

应用
应用	Anti-Hey 1/HRT1 Antibody detects level of Hey 1/HRT1 & has been published & validated for use in WB, IH.
主要应用	Immunohistochemistry Western Blotting
应用说明	Western blot: 1:200-1:1,000 using ECL. Immunohistochemistry: 1:200-1:1,000. Optimal working dilutions must be determined by the end user.

生物信息
免疫原品种	Synthetic peptide, amino acids 207-220 of human Hey 1 / HRT1.
宿主	Rabbit
特异性	Recognizes Hey 1 / HRT1, a Helix-loop-helix class of transcription factor.
品种反应性	MouseHuman
抗体类型	Polyclonal Antibody
Entrez基因编号	NM_012258.3 NM_001040708.1
Entrez基因汇总	This gene encodes a nuclear protein belonging to the hairy and enhancer of split-related (HESR) family of basic helix-loop-helix (bHLH)-type transcriptional repressors. Expression of this gene is induced by the Notch and c-Jun signal transduction pathways. Two similar and redundant genes in mouse are required for embryonic cardiovascular development, and are also implicated in neurogenesis and somitogenesis. Alternative splicing results in multiple transcript variants.
基因符号	HESR-1 HEY1 CHF-2 MGC1274 CHF2 HERP2 HRT1 hHRT1 HRT-1 HESR1 OAF1
UniProt编号	Q9Y5J3
UniProt汇总	FUNCTION: SwissProt: Q9Y5J3 # Downstream effector of Notch signaling which may be required for cardiovascular development. Transcriptional repressor which binds preferentially to the canonical E box sequence 5'- CACGTG-3'. Represses transcription by the cardiac transcriptional activators GATA4 and GATA6. SIZE: 304 amino acids; 32613 Da SUBUNIT: Self-associates (By similarity). Interacts with HES1 and HEYL (By similarity). Interacts with HDAC1, NCOR1 and SIN3A (By similarity). Interacts with GATA4 and GATA6 (By similarity). SUBCELLULAR LOCATION: Nucleus (By similarity). TISSUE SPECIFICITY: Expressed in the somitic mesoderm, the central nervous system, the kidney, the heart, nasal epithelium, and limbs. SIMILARITY: SwissProt: Q9Y5J3 ## Belongs to the HEY family. & Contains 1 basic helix-loop-helix (bHLH) domain. & Contains 1 Orange domain.

产品使用声明
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Maintain unopened vial at -70°C for up to 6 months. Avoid repeated freeze/thaw cycles. The rehydrated antibody solutions can be stored undiluted at 2-8°C for 2 months without any significant loss of activity. Note, the solution is not sterile, thus care should be taken if product is stored at 2-8°C. For storage at -20°C, the addition of an equal volume of glycerol can be used, however, it is recommended that ACS grade or higher glycerol be used, as significant loss of activity can occur if the glycerol used is not of high quality. For freezing, it is recommended that the rehydrated antibody solution be further diluted 1:1 with a 2% BSA (fraction V, highest-grade available) solution made with the rehydration buffer. The resulting 1% BSA/antibody solution can be aliquoted and stored frozen at -70°C for up to 6 months. Avoid repeated freeze/thaw cycles.

储存和货运信息

存储条件

Maintain unopened vial at -70°C for up to 6 months. Avoid repeated freeze/thaw cycles.

The rehydrated antibody solutions can be stored undiluted at 2-8°C for 2 months without any significant loss of activity. Note, the solution is not sterile, thus care should be taken if product is stored at 2-8°C.

For storage at -20°C, the addition of an equal volume of glycerol can be used, however, it is recommended that ACS grade or higher glycerol be used, as significant loss of activity can occur if the glycerol used is not of high quality.

For freezing, it is recommended that the rehydrated antibody solution be further diluted 1:1 with a 2% BSA (fraction V, highest-grade available) solution made with the rehydration buffer. The resulting 1% BSA/antibody solution can be aliquoted and stored frozen at -70°C for up to 6 months. Avoid repeated freeze/thaw cycles.

包装信息
数量	100 µg

merck millipore,默克密理博,AB5714,Anti-Hey 1/HRT1 Antibody

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