merck millipore,默克密理博,FCMAB208P,Milli-Mark™ Anti-CD79αcy-PE Antibody, clone HM57

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Merck Millipore 默克密理愽

品种反应性	主要应用	宿主	格式	抗体类型
H	FC	M	Phycoerythrin	Monoclonal Antibody

描述
产品目录编号	FCMAB208P
商名	Milli-Mark
描述	Milli-Mark™ Anti-CD79αcy-PE Antibody, clone HM57
Alternate Names	Membrane-bound immunoglobulin-associated protein B-cell antigen receptor complex-associated protein alpha chain Ig-alpha MB-1 membrane glycoprotein Surface IgM-associated protein
背景信息	CD79 is a disulphide-linked transmembrane heterodimer with a molecular mass of 82-95 kDa belonging to the immunoglobulin superfamily. It comprises the two glycoproteins, CD79α, with a molecular mass of 40-45 kDa, and CD79β, with a molecular mass of 37 kDa. CD79 is non-covalently associated with surface Ig, forming the B-cell receptor complex, which is required for antigen recognition. The expression of CD79 is largely restricted to B-lineage cells (Pilozzi,1998). In precursor B cells, the CD79 protein chains are already expressed in the cytoplasm (CyCD79). Surface expression of CD79 begins at the pro-B cell stage and persists throughout the B-cell differentiation. CD79α is more strongly expressed by B cells in the follicular mantle zone than by germinal centre B cells, suggesting that activation of mature B cells downregulates CD79 expression. CD79 expression ceases around the onset of plasma cell differentiation, with only a proportion of plasma cells containing CD79 (Comans-Bitter, 1997)(Nakamura, 1997). The HM57 antibody was clustered as Anti-CD79αcy at the Fifth International Workship on Human Leucocyte Differentiation Antigens (Engel, 1995).

产品信息
格式	Phycoerythrin
控制	Human Lymphocytes
演示	Purified Mouse monoclonal IgG1 conjugated to PE in 0.05M Tris-HCl buffer with 1% BSA, Sodium Azide at 0.097% at pH 7.2.

应用
应用	Milli-Mark Anti-CD79αcy-PE Antibody, clone HM57 is an antibody against CD79αcy for use in FC.
主要应用	Flow Cytometry

生物信息
免疫原品种	Synthetic peptide sequence comprising amino acids 202-216 of the CD79α protein. This oligopeptide represents an intra-cytoplasmic C-terminal part of the protein.
克隆	HM57
浓缩	Please refer to the Certificate of Analysis for the lot-specific concentration.
宿主	Mouse
特异性	Antibody recognizes Human CD79αcy antigen.
同种型	IgG1κ
品种反应性	Human
Species Reactivity Note	Tested and passed on Human.
抗体类型	Monoclonal Antibody
Entrez基因编号	NP_001774.1
纯化方法	Protein A purfied
UniProt编号	P11912

产品使用声明
质量保证	Evaluated by flow cytometry using human lymphocytes
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Maintained refrigerated at 2-8°C from date of receipt. Protected from light in undiluted aliquots for 6 months from date of receipt.

包装信息
数量	100 tests

merck millipore,默克密理博,FCMAB208P,Milli-Mark™ Anti-CD79αcy-PE Antibody, clone HM57

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