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品种反应性 主要应用 宿主 格式 抗体类型 R, H WB Rb Purified Polyclonal Antibody 描述 产品目录编号 ABN111 描述 Anti-RGS11 (CT) Antibody Alternate Names - RGS11
- Regulator of G-protein signaling 11
背景信息 Regulator of G-protein signaling 11 (RGS11) is a multidomain GTPase containing one each of DEP, RGS, and G-protein gamma domains. Like other members of the R7 RGS family, RGS11 uses these domains to form multisubunit complexes, which process the light responses of retinal cells. RGS11 interacts with the RGS9 anchor protein (R9AP) and the 5 G-protein beta subunit (Gbeta5) to form a trimeric complex that regulates the activity of the metabotropic glutamate receptor 6 (mGluR6) in ON-bipolar cells. The RGS11 complex hydrolyzes GTP and inactivates the G-protein Galphao, which is activated by mGluR6 in dark environments. By this mechanism, the RGS11 complex accelerates the light response in ON-bipolar retinal cells. 产品信息 格式 Purified 控制 - Human placenta tissue lysate
演示 Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. 应用 应用 Detect RGS11 (C-terminus) using this Anti-RGS11 (C-terminus) Antibody validated for use in Western Blotting. 主要应用 - Western Blotting
生物信息 免疫原品种 KLH-conjugated linear peptide corresponding to the C-terminus of human RGS11. 表位 C-terminus 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 特异性 This antibody recognizes the C-terminus of RGS11. 品种反应性 RatHuman 抗体类型 Polyclonal Antibody Entrez基因编号 - NP_003825
基因符号 - RGS11
纯化方法 Affinity purified UniProt编号 - O94810
产品使用声明 质量保证 Evaluated by Western Blot in human placenta tissue lysate.
Western Blot Analysis: 1 µg/mL of this antibody detected RGS11 in 10 µg of human placenta tissue lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
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