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品种反应性 主要应用 宿主 格式 抗体类型 H WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 ABF236 描述 Anti-SP110 Antibody Alternate Names - Speckled 110 kDa
- Transcriptional coactivator Sp110
- SP110
- Sp110 nuclear body protein
- Interferon-induced protein 41/75
背景信息 Sp110 nuclear body protein (SP110), or alternatively known as Interferon-induced protein 41/75, Speckled 110 kDa, or Transcriptional coactivator Sp110 is a transcription factor that is induced by interferon gamma as well as retinoic acid. It is highly expressed in leukocytes and spleen but also present in most other tissues as well including the brain, heart, and skeletal muscle. SP110 localizes to a structure within the nucleus called the nuclear body. The nuclear body is a multiprotein complex that appears to function as an enhancer for various genes; SP110 may also act as a nuclear hormone receptor and play some role in ribosome biogenesis as well as myeloid cell differentiation. Moreover, SP110 appears to play an important role in resistance to intracellular pathogens and immunity as several polymorphisms of the gene are associated with susceptibility to infection from various virus or pathogenic bacteria. EMD-Millipore’s Anti-SP110 rabbit polyclonal antibody has been tested in western blots on HeLa cell extracts. 产品信息 格式 Affinity Purified 演示 Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide and 50% glycerol. 应用 应用 Anti-SP110 Antibody is a highly specific rabbit polyclonal antibody, that targets Sp110 nuclear body protein (SP110) & has been tested in western blotting. 主要应用 - Western Blotting
生物信息 免疫原品种 GST-tagged fusion protein corresponding to human SP110. 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 品种反应性 Human 抗体类型 Polyclonal Antibody 基因符号 - SP110
纯化方法 Antigen Affinity purified UniProt编号 - Q9HB58
产品使用声明 质量保证 Evaluated by Western Blotting in HeLa cell lysate.
Western Blotting Analysis: A 1:800 dilution of this antibody detected SP110 in HeLa cell lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.包装信息 数量 150 µL
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