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重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 H WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 ABN59 Replaces 04-1054 描述 Anti-S100B Antibody Alternate Names - S100 calcium-binding protein B
- Protein S100-B
- S-100 protein beta chain
- S-100 protein subunit beta
背景信息 S-100 protein is a member of the EF-hand calcium-binding protein superfamily that is widely distributed and conserved in the central nervous system of vertebrates. The protein exists in both heterodimeric and homodimeric forms. The two subunits of S-100 protein are the products of separate genes that are differentially expressed by various cells. The beta subunit is present in all S-100 positive cells and tumors. In contrast, the alpha subunit is detectable only in heart, skeletal muscle and brain. In addition to its calcium binding properties, S-100 protein has a high-affinity binding site for zinc and is involved in the regulation of protein phosphorylation in the brain. The protein apparently plays a role in cell differentiation and growth, cytoskeletal structure and function, and has been implicated in neuropathological diseases. 产品信息 格式 Affinity Purified 演示 Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. 应用 应用 Detect S100 using this rabbit polyclonal antibody, Anti-S100B Antibody validated for use in western blotting & IHC (Paraffin). 主要应用 - Western Blotting
应用说明 Immunohistochemistry Analysis: A 1:2,000 dilution from a representative lot detected S100B in human thalamus and human cerebellum sections. 生物信息 免疫原品种 KLH-conjugated linear peptide corresponding to human S100B near the N-Terminus. 表位 Near N-Terminus 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 品种反应性 Human Species Reactivity Note Predicted to react with Mouse, Rat, Bovine, and Rhesus Macaque based on 100% sequence homology. 抗体类型 Polyclonal Antibody Entrez基因编号 - NP_006263
基因符号 - S100B
纯化方法 Affinity purified UniProt编号 - P04271
产品使用声明 质量保证 Evaluated by Western Blotting in A375 cell lysate.
Western Blotting Analysis: 0.1 µg/mL of this antibody detected S100B in 10 µg of A375 cell lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
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