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  • merck millipore,默克密理博,ABE532,Anti-acetyl Histone H4 (Lys12) Antibody

  • merck millipore,默克密理博,ABE532,Anti-acetyl Histone H4 (Lys12) Antibody

    产品名称：Anti-acetyl Histone H4 (Lys12) Antibody
    产品型号：ABE532
    Anti-acetyl Histone H4 (Lys12) Antibody is a highly specific rabbit polyclonal antibody, that targets Histone H4 & has been tested in western blotting & Dot Blot.

    merck millipore,默克密理博,ABE532,Anti-acetyl Histone H4 (Lys12) Antibody

  • 产品介绍
  • merck millipore,默克密理博,ABE532,Anti-acetyl Histone H4 (Lys12) Antibody

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    Yeast, HChIP, WBRbSerumPolyclonal Antibody
    描述
    产品目录编号 ABE532
    描述 Anti-acetyl Histone H4 (Lys12) Antibody
    Alternate Names
    • Histone H4
    背景信息 Histones are highly conserved proteins that serve as the structural scaffold for the organization of nuclear DNA into chromatin. The histones have an amino terminal tail, a globular domain, and a carboxy-terminal tail. The four core histones, H2A, H2B, H3 and H4 assemble into the octamer (2 molecules of each). Subsequently, 146 base pairs of DNA are wrapped in a sequence-independent manner around the octamer, forming the basic subunit of chromatin, the nucleosome. Histone H4 is one of the 5 main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N terminal tail H4 is involved with the structure of the nucleosomes of the 'beads on a string' structure. Acetylation of histone H4 occurs at several different lysine positions in the histone tail and is performed by a family of enzymes known as Histone Acetyl Transferases (HATs).
    产品信息
    格式 Serum
    演示 Rabbit polyclonal serum containing 0.0002% thimerosal.
    应用
    应用 Anti-acetyl Histone H4 (Lys12) Antibody is a highly specific rabbit polyclonal antibody, that targets Histone H4 & has been tested in western blotting & Dot Blot.
    主要应用
    • Chromatin Immunoprecipitation (ChIP)
    • Western Blotting
    应用说明 Dot Blot Analysis: A 1:500 dilution from a representative lot detected acetyl Histone H4 (Lys12) in a panel of Histone H2A, H2B, and H4 recombinant proteins.

    Chromatin Immunoprecipitation Analysis: A representative lot from an independent laboratory detected acetyl Histone H4 (Lys8) in certain yeast strains transfected with wildtype or mutant Histone H4 (Suka, N., et al. (2001). Mol Cell. 8(2):473-479.).
    生物信息
    免疫原品种 Ovalbumin-conjugated linear peptide corresponding to yeast Histone H4 acetylated at Lys12.
    宿主 Rabbit
    品种反应性 YeastHuman
    Species Reactivity Note Demonstrated to react with Human and Yeast. Predicted to react with Mouse and Rat based on 100% sequence homology.
    抗体类型 Polyclonal Antibody
    Entrez基因编号
    • NP_009563
    基因符号
    • HHF2
    • HHF1
    修改
    • Acetylation
    纯化方法 Unpurified
    UniProt编号
    • P02309
    产品使用声明
    质量保证 Evaluted by Western Blotting in HeLa cell lysate.

    Western Blotting Analysis: A 1:1,000 dilution from a representative lot detected acetyl Histone H4 (Lys12) in 10 µg of HeLa cell lysate.
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Stable for 1 year at -20°C from date of receipt.
    Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
    包装信息
    数量 100 µL

    merck millipore,默克密理博,ABE532,Anti-acetyl Histone H4 (Lys12) Antibody

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