merck millipore,默克密理博,ABE390,Anti-26S proteasome regulatory subunit RPN11 Antibody

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Merck Millipore 默克密理愽

品种反应性	主要应用	宿主	格式	抗体类型
M, H	WB	Rb	Purified	Polyclonal Antibody

描述
产品目录编号	ABE390
描述	Anti-26S proteasome regulatory subunit RPN11 Antibody
Alternate Names	26S proteasome-associated PAD1 homolog 1 26S proteasome non-ATPase regulatory subunit 14 26S proteasome regulatory subunit RPN11
背景信息	26S proteasome non-ATPase regulatory subunit 14 is also known as 26S proteasome regulatory subunit RPN11 or 26S proteasome-associated PAD1 homolog 1. It is the metalloprotease component of the 26S proteasome that specifically cleaves 'Lys-63'-linked polyubiquitin chains. 26S proteasome non-ATPase regulatory subunit 14 has a role in the response to double-strand breaks (DSBs) by regulating non-homologous end joining (NHEJ) via cleaving 'Lys-63'-linked polyubiquitin, retaining JMJD2A/KDM4A on chromatin and restricting TP53BP1 accumulation. 26S proteasome non-ATPase regulatory subunit 14 is also involved in homologous recombination repair by promoting RAD51 loading. 26S proteasome non-ATPase regulatory subunit 14 is widely expressed, but found in the highest levels in heart and skeletal muscle.

产品信息
格式	Purified
控制	HeLa cell lysate
演示	Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

应用
应用	Anti-26S proteasome regulatory subunit RPN11 is an antibody targeting the 26S proteasome regulatory subunit RPN11 protein, validated for use in WB.
主要应用	Western Blotting

生物信息
免疫原品种	KLH-conjugated linear peptide corresponding to the C-terminus of human 26S proteasome regulatory subunit RPN11.
表位	C-terminus
浓缩	Please refer to the Certificate of Analysis for the lot-specific concentration.
宿主	Rabbit
特异性	This antibody recognizes the C-terminus of 26S proteasome regulatory subunit RPN11.
品种反应性	MouseHuman
Species Reactivity Note	Demonstrated to react with Human. Predicted to react with Mouse based on 100% sequence homology.
抗体类型	Polyclonal Antibody
Entrez基因编号	NP_005796
基因符号	POH1 PSMD14
纯化方法	Protein A purified
UniProt编号	O00487

产品使用声明
质量保证	Evaluated by Western Blotting in HeLa cell lysate. Western Blotting Analysis: 0.5 µg/mL of this antibody detected 26S proteasome regulatory subunit RPN11 in 10 µg of HeLa cell lysate.
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Stable for 1 year at 2-8°C from date of receipt.

包装信息
数量	100 µg

merck millipore,默克密理博,ABE390,Anti-26S proteasome regulatory subunit RPN11 Antibody

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