merck millipore,默克密理博,GF110,Fibroblast Growth Factor-8 Protein, Recombinant human

搜索"Merck Millipore 密理愽"产品

Merck Millipore 默克密理愽

当前位置：首页 > >Merck Millipore > 生命科学研究
生命科学研究

merck millipore,默克密理博,GF110,Fibroblast Growth Factor-8 Protein, Recombinant human
产品名称：Fibroblast Growth Factor-8 Protein, Recombinant human
产品型号：GF110
The Fibroblast Growth Factor-8 (or FGF-8 protein) is a heparin binding growth factor that stimulates the proliferation & activation of cells that express FGF receptors.

merck millipore,默克密理博,GF110,Fibroblast Growth Factor-8 Protein, Recombinant human

产品介绍

merck millipore,默克密理博,GF110,Fibroblast Growth Factor-8 Protein, Recombinant human

重要规格表

主要应用	品种	来源	纯度
CULT	Human	E.coli	Greater than 95% by SDS-PAGE and HPLC analysis. Endotoxin level is less than 0.1 ng per μg (1EU/ug) of FGF-8.

描述
产品目录编号	GF110
品牌系列	Chemicon®
商名	Chemicon
描述	Fibroblast Growth Factor-8 Protein, Recombinant human
概述	Fibroblast Growth Factor-8 (FGF-8) is a heparin binding growth factor that stimulates the proliferation and activation of cells that express FGF receptors. Recombinant Human FGF-8 is a 22.4 kDa protein containing 193 amino residues.
Alternate Names	FGF-8

产品信息
演示	The sterile filtered solution was lyophilized from 5 mM NaP, pH 7.5 + 5mM NaCl.

应用
应用	The Fibroblast Growth Factor-8 (or FGF-8 protein) is a heparin binding growth factor that stimulates the proliferation & activation of cells that express FGF receptors.
主要应用	Cell Culture

生物信息
纯度	Greater than 95% by SDS-PAGE and HPLC analysis. Endotoxin level is less than 0.1 ng per μg (1EU/ug) of FGF-8.
来源	E.coli
品种	Human
特异活性	The ED(50) was determined by the dose-dependent stimulation of thymidine uptake by BaF3 cells expressing FGF receptors is <=0.5 ng/ml, corresponding to a specific activity of >= 1 x 10(E6) units/mg. The protein may appear as a haze or film, which you may not see at the bottom of the vial.
Entrez基因编号	NM_033165.1 NM_006119.2 NM_033163.1 NM_033164.1
Entrez基因汇总	The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein is known to be a factor that supports androgen and anchorage independent growth of mammary tumor cells. Overexpression of this gene has been shown to increase tumor growth and angiogensis. The adult expression of this gene is restricted to testes and ovaries. Temporal and spatial pattern of this gene expression suggests its function as an embryonic epithelial factor. Studies of the mouse and chick homologs revealed roles in midbrain and limb development, organogenesis, embryo gastrulation and left-right axis determination. The alternative splicing of this gene results in four transcript variants.
基因符号	AIGF FGF8 MGC149376 HBGF-8 FGF-8
UniProt编号	P55075
UniProt汇总	FUNCTION: SwissProt: P55075 # Stimulates growth of the cells in an autocrine manner. Mediates hormonal action on the growth of cancer cells. SIZE: 233 amino acids; 26525 Da SUBCELLULAR LOCATION: Secreted. DEVELOPMENTAL STAGE: In adults expression is restricted to the gonads. SIMILARITY: SwissProt: P55075 ## Belongs to the heparin-binding growth factors family.

产品使用声明
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	The lyophilized powder is stable for a few weeks at room temperature, but best stored at -20°C for up to 12 months after date of receipt. After a quick spin, reconstitute with 10 mM Tris, pH 8.0 to a concentration of 0.1-1.0 mg/mL. This solution can then be diluted into other aqueous buffers and stored at 4ºC for 1 week or -20ºC for future use. Reconstituted human FGF-8 should be stored in undiluted aliquots at -20ºC for upt to 6 months. Avoid repeated freeze/thaw cycles.

储存和货运信息

存储条件

The lyophilized powder is stable for a few weeks at room temperature, but best stored at -20°C for up to 12 months after date of receipt. After a quick spin, reconstitute with 10 mM Tris, pH 8.0 to a concentration of 0.1-1.0 mg/mL. This solution can then be diluted into other aqueous buffers and stored at 4ºC for 1 week or -20ºC for future use. Reconstituted human FGF-8 should be stored in undiluted aliquots at -20ºC for upt to 6 months. Avoid repeated freeze/thaw cycles.