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品种反应性 主要应用 宿主 格式 抗体类型 M IHC, WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 ABC834 描述 Anti-ZIP-6 Antibody Alternate Names - ZIP-6
- Zinc transporter ZIP6
- Estrogen-regulated protein LIV-1
- Solute carrier family 39 member 6
- Zrt- and Irt-like protein 6
背景信息 Zinc transporter ZIP6, also known as Estrogen-regulated protein LIV-1 or Solute carrier family 39 member 6 orZrt- and Irt-like protein 6 (ZIP-6), and encoded by the gene name ZIP6 or SLC39A6 or LIV1 is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. ZIP-6 was initially identified as LIV-1, an estrogen-regulated gene that has been implicated in metastatic breast cancer. Elevated ZIP-6 expression has also been reported in human cervical cancer and the HeLa cell line; down-regulation of ZIP-6 expression in HeLa by RNAi inhibited cell proliferation, colony formation, migration and invasiveness, as well as decreasing Snail and Slug levels, suggesting ZIP-6 plays a regulatory role on the ERK1/2-Snail/Slug pathway. 产品信息 格式 Affinity Purified 演示 Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide. 应用 应用 Anti-ZIP-6 Antibody detects level of ZIP-6 & has been published & validated for use in ZIP-6. 主要应用 - Immunohistochemistry
- Western Blotting
应用说明 Immunohistochemistry Analysis: 5 μg/mL from a representative lot detected Anti-ZIP-6 in mouse lung tissue. 生物信息 免疫原品种 KLH-conjugated synthetic peptide corresponding to the center region of human Anti-ZIP-6. 表位 center region 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 特异性 This antibody is recognizes isoforms at ~48 and ~85 kDa and is predicted to not cross-react with other ZIP family members. 品种反应性 Mouse 抗体类型 Polyclonal Antibody 基因符号 - ZIP6
- SLC39A6
- LIV1
纯化方法 Antigen Affinity purified UniProt编号 - Q13433
产品使用声明 质量保证 Evaluated by Western Blotting in mouse lung tissue lysate.
Western Blotting Analysis: 1 μg/mL of this antibody detected Anti-ZIP-6 in mouse lung tissue lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
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