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品种反应性 主要应用 宿主 格式 抗体类型 H IHC, WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 ABC379 描述 Anti-ACVRL1 Antibody 背景信息 The protein receptor named Serine/threonine protein kinase receptor R3 (SKR3), or Activin receptor-like kinase 1 (ALK-1), or TGF-beta superfamily receptor type 1 (TSR-1), and encoded by the human gene named ACVRL1/ACVRLK1/ALK1 is the receptor for BMP9/GDF2 and BMP10 and plays an important role in normal blood vessel development. ACVRL1 is expressed by endothelial cells and other tissues. Expression of ACVRL1 in cancers correlates with advanced cancer and invasion characteristics so ACVRL1 expression levels are being examined as a prognostic marker for cancer as well as target for anti-cancer therapy. EMD-Millipore’s Ant- ACVRL1 rabbit polyclonal antibody has been tested in western blot on Jurkat cell extracts on in paraffin embedded immunohistochemistry on human lymphoma tissues sections. 产品信息 格式 Affinity Purified 演示 Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide and 50% glycerol. 应用 应用 Detect Activin receptor-like kinase 1 using this rabbit polyclonal antibody, Anti-ACVRL1 Antibody validated for use in western blotting & IHC. 主要应用 - Immunohistochemistry
- Western Blotting
应用说明 Immunohistochemistry Analysis: A 1:50 dilution from a representative lot detected ACVRL1 in human lymphoma tissue. 生物信息 免疫原品种 GST-tagged fusion protein corresponding to human ACVRL1. 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 品种反应性 Human 抗体类型 Polyclonal Antibody 基因符号 - ALK1
- ACVRL1
- ACVRLK1
纯化方法 Antigen Affinity purified UniProt编号 - P37023
产品使用声明 质量保证 Evaluated by Western Blotting in Jurkat cell lysate.
Western Blotting Analysis: A 1:400 dilution of this antibody detected ACVRL1 in Jurkat cell lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.包装信息 数量 150 µL
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