merck millipore,默克密理愽
  • merck millipore,默克密理博,05-1540,Anti-Gemin2 Antibody, clone 2E17

  • merck millipore,默克密理博,05-1540,Anti-Gemin2 Antibody, clone 2E17

    产品名称：Anti-Gemin2 Antibody, clone 2E17
    产品型号：05-1540
    Anti-Gemin2 Antibody, clone 2E17 is a Mouse Monoclonal Antibody for detection of Gemin2 also known as SMN interacting protein 1-delta & has been validated in WB, ICC, ELISA & IP.

    merck millipore,默克密理博,05-1540,Anti-Gemin2 Antibody, clone 2E17

  • 产品介绍
  • merck millipore,默克密理博,05-1540,Anti-Gemin2 Antibody, clone 2E17

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    M, HELISA, WB, ICCMPurifiedMonoclonal Antibody
    描述
    产品目录编号 05-1540
    描述 Anti-Gemin2 Antibody, clone 2E17
    Alternate Names
    • survival of motor neuron protein interacting protein
    • GEMIN2
    • Gemin2
    • Component of gems
    • SMN interacting protein 1-delta
    • SMN-interacting protein 1
    • survival interacting protein 1
    背景信息 Gemin-2 (also known as SIP1 or SMN interacting protein1) is a part of the SMN complex. The SMN complex plays a role in RNA metabolism and in splicing regulation. As part of the SMN complex Gemin-2 interacts directly with Gemin-5 in a heteromeric complex that includes Gemin-3, Gemin-4, Gemin-6. This macromolecular complex (SMN complex) mediates assembly of spliceosomal snRNA complexes containing U1 and U5.
    产品信息
    格式 Purified
    控制
    • HeLa cell lysates.
    演示 Purified mouse IgG1κ supernatant in buffer containing 0.1 M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.05% sodium azide
    应用
    应用 Anti-Gemin2 Antibody, clone 2E17 is a Mouse Monoclonal Antibody for detection of Gemin2 also known as SMN interacting protein 1-delta & has been validated in WB, ICC, ELISA & IP.
    主要应用
    • ELISA
    • Western Blotting
    • Immunocytochemistry
    应用说明 Immunocytochemistry:
    Cited in Battle, D.J., et. al (2007). J. Biol. Chem. 282: 27953 - 27959 and Zhang, Z., et. al (2008). Cell, 133:85-600. using a representative lot.
    ELISA:
    Cited in Zhang, Z., et. al (2008). Cell, 133:85-600.
    Immunoprecipitation:
    Cited in Battle, D.J., et. al(2007). J. Biol. Chem. 282: 27953 - 27959 using a representative lot.
    生物信息
    免疫原品种 His-tagged recombinant protein corresponding to human Gemin-2.
    表位 N/A
    克隆 2E17
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Mouse
    特异性 Antibody recognizes Gemin-2.
    同种型 IgG1κ
    品种反应性 MouseHuman
    Species Reactivity Note Reacts with Human. Predicted to recognize mouse based on 100% sequence homology.
    抗体类型 Monoclonal Antibody
    Entrez基因编号
    • NM_001009182.1
    基因符号
    • SIP1-delta
    • SIP1
    纯化方法 Protein G purfied
    UniProt编号
    • O14893
    UniProt汇总 Function The SMN complex plays an essential role in spliceosomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing in the nucleus.

    Subunit structure Part of the core SMN complex that contains SMN1, SIP1/GEMIN2, DDX20/GEMIN3, GEMIN4, GEMIN5, GEMIN6, GEMIN7, GEMIN8 and STRAP/UNRIP. Interacts directly with GEMIN5.
    产品使用声明
    质量保证 Evaluated by Western Blotting in HeLa cell lysates.

    Western Blotting Analysis: 0.5 µg/mL of this antibody detected Gemin-2 in HeLa cell lysates.
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Stable for 1 year at 2-8°C from date of receipt.
    包装信息
    数量 100 µg

    merck millipore,默克密理博,05-1540,Anti-Gemin2 Antibody, clone 2E17

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