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merck millipore,默克密理博,FCMAB218F,Milli-Mark Anti-CD19-FITC Antibody, clone 6D5
产品名称：Milli-Mark Anti-CD19-FITC Antibody, clone 6D5
产品型号：FCMAB218F
Detect CD19 using this Milli-Mark Anti-CD19-FITC Antibody, clone 6D5 validated for use in FC.
merck millipore,默克密理博,FCMAB218F,Milli-Mark Anti-CD19-FITC Antibody, clone 6D5
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 M FC R FITC Monoclonal Antibody 描述 产品目录编号 FCMAB218F 商名 - Milli-Mark
描述 Milli-Mark® Anti-CD19-FITC Antibody, clone 6D5 Alternate Names - B4, Leu-12
- B-lymphocyte antigen CD19
- Differentiation antigen CD19
背景信息 CD19 is a member of the immunoglobulin superfamily which is expressed throughout B lymphocyte development, from early pro-B cell stages and into the mature B-cell stages during development. Also known as B4, CD19+ expression is found on mouse splenic and peritoneal IgM+ cells of both B-1 and B-2 lineages, with B-1 cells expressing higher levels of CD19 than B-2 cells in these sites. CD19 plays an integral role in B lymphocyte development, B-cell activation, and in the maturation of memory B cells. Monoclonal antibody 6D5 recognizes the same epitope as the published clone, 1D3. 产品信息 格式 FITC 控制 - mouse splenocytes
演示 Purified rat monoclonal IgG2ak conjugated to FITC in PBS with 0.1% sodium azide and 15 mg/mL BSA. 应用 应用 Detect CD19 using this Milli-Mark Anti-CD19-FITC Antibody, clone 6D5 validated for use in FC. 主要应用 - Flow Cytometry
生物信息 免疫原品种 Full-length murine CD19 cDNA cloned into a vector and expressed in K562 human erythroleukemia cells. 克隆 6D5 宿主 Rat 特异性 Antibody recognizes mouse CD19. 同种型 IgG2aκ 品种反应性 Mouse Species Reactivity Note Tested and passed on Mouse. 抗体类型 Monoclonal Antibody Entrez基因编号 - NP_033974
基因符号 - Cd19
纯化方法 Protein G Purified UniProt编号 - P25918
UniProt汇总 FUNCTION: Assembles with the antigen receptor of B lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation.
SUBUNIT STRUCTURE: Forms a complex with CD21, CD81 and CD225 in the membrane of mature B cells. Interacts with VAV. Interacts with GRB2 and SOS when phosphorylated on Tyr-346 and/or Tyr-376. Interacts with PLCG2 when phosphorylated on Tyr-402 By similarity.
SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.
POST-TRANSLATIONAL MODIFICATION: Phosphorylated upon DNA damage, probably by ATM or ATR.
SEQUENCE SIMILARITIES: Contains 2 Ig-like C2-type (immunoglobulin-like) domains.产品使用声明 质量保证 Evaluated by flow cytometry using mouse splenocytes. 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Maintain refrigerated at 2-8 °C protected from light in undiluted aliquots for up to 6 months from date of receipt. 包装信息 数量 100 tests
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