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  • merck millipore,默克密理博,ABC23,Anti-ATG9 Antibody

  • merck millipore,默克密理博,ABC23,Anti-ATG9 Antibody

    产品名称：Anti-ATG9 Antibody
    产品型号：ABC23
    This Anti-ATG9 Antibody is validated for use in WB, IH(P) for the detection of ATG9.

    merck millipore,默克密理博,ABC23,Anti-ATG9 Antibody

  • 产品介绍
  • merck millipore,默克密理博,ABC23,Anti-ATG9 Antibody

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    Ca, H, M, R, Rhesus Macaque, ChpWBRbAffinity PurifiedPolyclonal Antibody
    描述
    产品目录编号 ABC23
    描述 Anti-ATG9 Antibody
    Alternate Names
    • mATG9
    • Autophagy-related protein 9A
    • APG9-like 1
    背景信息 ATG9 (autophagy-related 9) is an integral membrane protein that is necessary for autophagy and the cytoplasm-to-vacuole pathway. It moves from the Golgi to the endosomes, which indicates the Golgi's role in the autophagic pathway. ATG9 has been implicated as a membrane carrier. ATG9 is required for the formation of the phagophore assembly site.
    产品信息
    格式 Affinity Purified
    控制
    • Jurkat cell lysate
    演示 Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
    应用
    应用 This Anti-ATG9 Antibody is validated for use in WB, IH(P) for the detection of ATG9.
    主要应用
    • Western Blotting
    应用说明 Immunohistochemistry Analysis: A 1:600 dilution from a representative lot detected ATG9 in metastatic breast carcinoma in the brain, Hodgkin's Lymphoma, B-cell lymphoma, renal carcinoma, and kidney clear cell carcinoma tissues.
    生物信息
    免疫原品种 KLH-conjugated linear peptide corresponding to the lumenal region of human ATG9.
    表位 Lumenal Region
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Rabbit
    特异性 This antibody recognizes isoform 1 of ATG9.
    品种反应性 CanineHumanMouseRatRhesus MacaqueChimpanzee
    Species Reactivity Note Demonstrated to react with Human.
    Predicted to react with Mouse, Rat, Rhesus Macaque, Chimpanzee, and Canine based on 100% sequence homology.
    抗体类型 Polyclonal Antibody
    Entrez基因编号
    • NP_001070666
    基因符号
    • APG9L1
    • ATG9A
    纯化方法 Affinity Purified
    UniProt编号
    • Q7Z3C6
    UniProt汇总 FUNCTION: Plays a role in autophagy. Cycles between a juxta-nuclear trans-Golgi network compartment and late endosomes. Nutrient starvation induces accumulation on autophagosomes. Starvation-dependent trafficking requires ULK1, ATG13 and FAM48A.

    SUBUNIT STRUCTURE: Interacts with FAM48A.

    SUBCELLULAR LOCATION: Cytoplasmic vesicle › autophagosome membrane; Multi-pass membrane protein (By similarity). Golgi apparatus › trans-Golgi network membrane; Multi-pass membrane protein. Late endosome membrane; Multi-pass membrane protein Ref.8.

    SEQUENCE SIMILARITIES: Belongs to the ATG9 family.

    SEQUENCE CAUTION: The sequence BAB13882.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.

    The sequence BAB15246.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.

    The sequence BAB55119.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.
    产品使用声明
    质量保证 Evaluated by Western Blot in Jurkat cell lysate.

    Western Blot Analysis: 0.1 µg/mL of this antibody detected ATG9 in 10 µg of Jurkat cell lysate.
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Stable for 1 year at 2-8°C from date of receipt.
    包装信息
    数量 100 µg

    merck millipore,默克密理博,ABC23,Anti-ATG9 Antibody

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