merck millipore,默克密理愽
  • merck millipore,默克密理博,20-125,cdc2 Substrate Cocktail

  • merck millipore,默克密理博,20-125,cdc2 Substrate Cocktail

    产品名称：cdc2 Substrate Cocktail
    产品型号：20-125
    This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S & G2/M phase transitions of eukaryotic cell cycl More>>

    merck millipore,默克密理博,20-125,cdc2 Substrate Cocktail

  • 产品介绍
  • merck millipore,默克密理博,20-125,cdc2 Substrate Cocktail

    重要规格表

    主要应用
    KA
    描述
    产品目录编号 20-125
    品牌系列 Upstate
    商名
    • Upstate
    描述 cdc2 Substrate Cocktail
    产品信息
    演示 20mM MOPS, pH 7.2, 25mM β-glycerophosphate, 5mM EGTA, 1mM sodium orthovanadate, 1mM dithiothreitol.
    应用
    应用 This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S & G2/M phase transitions of eukaryotic cell cycle.
    主要应用
    • Kinase Assay
    应用说明 For use in kinase assays.
    生物信息
    Entrez基因编号
    • NM_033379.2
    • NM_001786.2
    Entrez基因汇总 The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control.
    基因符号
    • DKFZp686L20222
    • CDC2
    • MGC111195
    • CDK1
    • CDC28A
    UniProt编号
    • P06493
    UniProt汇总 FUNCTION: SwissProt: P06493 # Plays a key role in the control of the eukaryotic cell cycle. It is required in higher cells for entry into S-phase and mitosis. p34 is a component of the kinase complex that phosphorylates the repetitive C-terminus of RNA polymerase II.
    SIZE: 297 amino acids; 34095 Da
    SUBUNIT: Forms a stable but non-covalent complex with a regulatory subunit and with a cyclin. Interacts with DLG7. Isoform 2 is unable to complex with cyclin B1 and also fails to bind to the CDK inhibitor p21. Interacts with catalytically active CCNB1 and RALBP1 during mitosis to form an endocytotic complex during interphase.
    SUBCELLULAR LOCATION: Nucleus (By similarity).
    SIMILARITY: SwissProt: P06493 ## Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily. & Contains 1 protein kinase domain.
    产品使用声明
    销售限制 This product is derived from bovine source. Export of this product to certain countries may be restricted. Please contact Customer Service or your local distributor to inquire about product availability and export options.
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 1 year at -20°C
    包装信息
    数量 1 mL

    merck millipore,默克密理博,20-125,cdc2 Substrate Cocktail

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