- 当前位置：首页 > >Merck Millipore > 生命科学研究
- 生命科学研究
-
-
merck millipore,默克密理博,219479,Cdc2-Like Kinase Inhibitor, TG003 - CAS 300801-52-9 - Calbiochem
产品名称：Cdc2-Like Kinase Inhibitor, TG003 - CAS 300801-52-9 - Calbiochem
产品型号：219479
The Cdc2-Like Kinase Inhibitor, TG003, also referenced under CAS 300801-52-9, controls the biological activity of Cdc2-Like. This small molecule/inhibitor is primarily used for Phosphorylation & Depho More>>
merck millipore,默克密理博,219479,Cdc2-Like Kinase Inhibitor, TG003 - CAS 300801-52-9 - Calbiochem
- 产品介绍
重要规格表
经验配方 CAS号 C₁₃H₁₅NO₂S 300801-52-9 描述 概述 A cell-permeable dihydrobenzothiazolo compound that acts as a potent, specific, reversible, and ATP-competitive inhibitor of Clk-family of kinases (Ki = 10 nM for mClk1/Sty; IC50 = 15 nM, 20 nM, 200 nM, and > 10 µM for mClk4, mClk1, mClk2, and mClk3, respectively). Does not affect the activities of SRPK1, SRPK2, PKA, or PKC up to 1 µM. Shown to alter the regulation of alternative splicing mediated by phosphorylation of Ser/Arg-rich (SR) proteins both in vitro and in vivo. Suppresses early Xenopus developmental abnormality induced by excess levels of Clk-activity. 产品目录编号 219479 品牌系列 Calbiochem®
同义词 (Z)-1-(3-Ethyl-5-methoxy-2,3-dihydrobenzothiazol-2-ylidene)propan-2-one, Clk Inhibitor, TG003 参考 参考 Muraki, M., et al. 2004. J. Biol. Chem. 279, 24246. 产品信息 CAS号 300801-52-9 具有ATP竞争性 Y 形式 Off-white solid Hill配方 C₁₃H₁₅NO₂S 化学配方 C₁₃H₁₅NO₂S Molar Mass 249.3 可逆 Y 结构配方图像 生物信息 主靶 mClk4, mClk1, mClk2, mClk3 主靶IC50 15 nM, 20 nM, 200 nM, >10 µM for mClk4, mClk1, mClk2, and mClk3, respectively 主靶Ki 10 nM 纯度 ≥98% by HPLC 理化信息 细胞可渗透 Y 溶解度 DMSO or MeOH 储存和货运信息 货运代码 Ambient Temperature Only
毒性 Standard Handling
储存 +2°C to +8°C
避光 Protect from light
无需冷冻 No
特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C. 包装信息 惰性气体下包装 Packaged under inert gas
上一件merck millipore产品：merck millipore,默克密理博,TMS-006-B,EmbryoMax Ultra Pure Water, sterile H2O, 500ml
下一件merck millipore产品：merck millipore,默克密理博,AB2290A4,Anti-MAP2, Alexa Fluor 488 Conjugate Antibody
相关产品
merck millipore,默克密理博,ABC23,Anti-ATG9 Antibody
merck millipore,默克密理博,14-329M,JNK2α2/SAPK1a Protein, active, 250 µg
merck millipore,默克密理博,SF-111,Twist; Human, Cyanine 3, RNA Detection Probe,SmartFlare
merck millipore,默克密理博,SF-1696,GATA2; Human, Cyanine 3 RNA Detection Probe,SmartFlare
merck millipore,默克密理博,TMS-006-B,EmbryoMax Ultra Pure Water, sterile H2O, 500ml
merck millipore,默克密理博,AB2290A4,Anti-MAP2, Alexa Fluor 488 Conjugate Antibody
merck millipore,默克密理博,SF-1749,ING4; Human, Cyanine 5 RNA Detection Probe,SmartFlare
merck millipore,默克密理博,CC1092,Integrin α3β1, Octyl-β-D-glucopyranoside Formulation, Human
merck millipore,默克密理博,SF-871,miR-708-5p; Human, Cyanine 5, RNA Detection Probe,SmartFlare
