- 当前位置：首页 > >Merck Millipore > 生命科学研究
- 生命科学研究
-
-
merck millipore,默克密理博,ABC155,Anti-MDC1 Antibody
产品名称：Anti-MDC1 Antibody
产品型号：ABC155
Anti-MDC1 Antibody is a highly specific rabbit polyclonal antibody, that targets MDC1 (Mediator of DNA damage checkpoint protein 1) & has been tested in western blotting, ICC & IP.
merck millipore,默克密理博,ABC155,Anti-MDC1 Antibody
- 产品介绍
重要规格表
品种反应性 主要应用 宿主 格式 抗体类型 H ICC, WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 ABC155 描述 Anti-MDC1 Antibody Alternate Names - Nuclear factor with BRCT domains 1
- Mediator of DNA damage checkpoint protein 1
背景信息 Mediator of DNA damage checkpoint protein 1 (MDC1) is a subunit of the cohesin complex and is an essential protein required for sister chromatid cohesion in mitosis and meiosis. Temperature-sensitive mutations of this protein have been associated with defects in sister chromatid cohesion, chromosome condensation, and chromosome segregation. Its expression is cell cycle regulated and peaks in S phase. Expression of MDC1 is required for the S- and G2/M-checkpoint-mediated cell cycle arrest in response to DNA damage. MDC1 has been shown to interact with H2A.X near sites of DNA double-strand breaks and recruit ATM kinase to the damaged region of DNA. Consistent with this role, MDC1 also appears to modulate the function of other proteins involved in the DNA damage checkpoint such as BRCA1 and Chk2. 产品信息 格式 Affinity Purified 控制 - HeLa cells
演示 Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. 应用 应用 Anti-MDC1 Antibody is a highly specific rabbit polyclonal antibody, that targets MDC1 (Mediator of DNA damage checkpoint protein 1) & has been tested in western blotting, ICC & IP. 主要应用 - Immunocytochemistry
- Western Blotting
应用说明 Immunoprecipitation Analysis: 10 µg from a representative lot detected MDC1 in 0.5 mg of HEK293 nuclear extract.
Western Blotting Analysis: 2 µg/mL from a representative lot detected MDC1 in 10 µg of HEK293 nuclear extract.生物信息 免疫原品种 KLH-conjugated linear peptide corresponding to the human MDC1. 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 品种反应性 Human Species Reactivity Note Demonstrated to react with Human. Predicted to react with Chimpanzee based on 100% sequence homology. 抗体类型 Polyclonal Antibody Entrez基因编号 - NP_055456
基因符号 - MDC1
纯化方法 Affinity purified UniProt编号 - Q14676
产品使用声明 质量保证 Evaluated by Immunocytochemistry in HeLa cells.
Immunocytochemistry Analysis: A 1:500 dilution from a representative lot detected MDC1 in 10 µg of HeLa cells.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
上一件merck millipore产品：merck millipore,默克密理博,HTS020M,ChemiSCREEN™ Membrane Preparation Recombinant Human CB2 Cannabinoid Receptor
下一件merck millipore产品：merck millipore,默克密理博,AB110,Anti-PNMT Antibody
相关产品
merck millipore,默克密理博,07-807,Anti-phospho-Met (Tyr1003) Antibody
merck millipore,默克密理博,AB932,Anti-Glucagon Antibody
merck millipore,默克密理博,ABT29,Anti-Tensin-3 Antibody
merck millipore,默克密理博,05-522,Anti-SRC-1 Antibody, clone 1135
merck millipore,默克密理博,AB110,Anti-PNMT Antibody
merck millipore,默克密理博,MABN1047,Anti-CD52 Antibody, clone EPR3153(2), rabbit monoclonal
merck millipore,默克密理博,3750-OP,OmniPur DNase I, Bovine Pancreas - Calbiochem
merck millipore,默克密理博,203697,BPDQ - CAS 169205-87-2 - Calbiochem
