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品种反应性 主要应用 宿主 格式 抗体类型 H IH(P) Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 AB9141 品牌系列 Chemicon®
商名 - Chemicon
描述 Anti-Dopamine Receptor D1 Antibody 产品信息 格式 Affinity Purified 演示 Affinity purified immunoglobulin. Liquid in PBS, pH 7.7 with 0.01% sodium azide. 应用 应用 This Anti-Dopamine Receptor D1 Antibody is validated for use in IH(P) for the detection of Dopamine Receptor D1. 主要应用 - Immunohistochemistry (Paraffin)
应用说明 Immunohistochemistry on formalin fixed paraffin embedded tissue sections.
Optimal working dilutions must be determined by the end user.生物信息 免疫原品种 Synthetic peptide from the C-terminal domain of human Dopamine Receptor D1. The immunogen has 94% conservation with rat and 88% with mouse. 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 特异性 Recognizes Dopamine Receptor D1. 品种反应性 Human 抗体类型 Polyclonal Antibody Entrez基因编号 - NM_000794.3
Entrez基因汇总 This gene encodes the D1 subtype of the dopamine receptor. The D1 subtype is the most abundant dopamine receptor in the central nervous system. This G-protein coupled receptor stimulates adenylyl cyclase and activates cyclic AMP-dependent protein kinases. D1 receptors regulate neuronal growth and development, mediate some behavioral responses, and modulate dopamine receptor D2-mediated events. Alternate transcription initiation sites result in two transcript variants of this gene. 基因符号 - DADR
- DRD1
- D
- DRD1A
UniProt编号 - P21728
UniProt汇总 FUNCTION: SwissProt: P21728 # This is one of the five types (D1 to D5) of receptors for dopamine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.
SIZE: 446 amino acids; 49293 Da
SUBUNIT: Interacts with DNAJC14 via its C-terminus (By similarity). Interacts with DRD1IP.
SUBCELLULAR LOCATION: Cell membrane; Multi-pass membrane protein (By similarity). Endoplasmic reticulum membrane; Multi-pass membrane protein (By similarity). Note=Transport from the endoplasmic reticulum to the cell surface is regulated by interaction with DNAJC14 (By similarity).
TISSUE SPECIFICITY: Detected in caudate, nucleus accumbens and in the olfactory tubercle.
SIMILARITY: SwissProt: P21728 ## Belongs to the G-protein coupled receptor 1 family.产品使用声明 销售限制 This product is not available for sale in Japan. 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Maintain at -70°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles. 包装信息 数量 50 µg
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