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品种反应性 主要应用 宿主 格式 抗体类型 R WB, ELISA Rb Serum Polyclonal Antibody 描述 产品目录编号 AB5948 品牌系列 Chemicon®
商名 - Chemicon
描述 Anti-GABA A Receptor α2 Antibody 产品信息 格式 Serum 演示 Rabbit serum. Liquid. 应用 应用 Detect GABA A Receptor α2 using this Anti-GABA A Receptor α2 Antibody validated for use in ELISA, IP & WB. 主要应用 - Western Blotting
- ELISA
应用说明 Western blot: 1:1,000-1:2,500. Recognizes a 53 kDa protein.
Immunoprecipitation
ELISA
Optimal working dilutions must be determined by end user.生物信息 免疫原品种 Synthetic peptide from rat GABA-A receptor alpha 2 subunit from the C-terminus. 宿主 Rabbit 特异性 GABA-A receptor alpha 2 subunit. No known cross reactivity with other GABA-A receptor subunits. 品种反应性 Rat 抗体类型 Polyclonal Antibody Entrez基因编号 - NM_000807.1
Entrez基因汇总 GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. Alternatively spliced transcript variants encoding the same protein have been found for this gene. 基因符号 - GABA
- GABRA2
UniProt编号 - P47869
UniProt汇总 FUNCTION: SwissProt: P47869 # GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.
SIZE: 451 amino acids; 51326 Da
SUBUNIT: Binds UBQLN1 (By similarity). Generally pentameric. There are five types of GABA(A) receptor chains: alpha, beta, gamma, delta, and rho.
SUBCELLULAR LOCATION: Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein.
SIMILARITY: SwissProt: P47869 ## Belongs to the ligand-gated ionic channel (TC 1.A.9) family.产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Maintain frozen at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles. 包装信息 数量 50 µL
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