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  • merck millipore,默克密理博,AB5430P,Anti-Per3 Antibody

  • merck millipore,默克密理博,AB5430P,Anti-Per3 Antibody

    产品名称：Anti-Per3 Antibody
    产品型号：AB5430P
    Anti-Per3 Antibody is an antibody against Per3 for use in ELISA & WB.

    merck millipore,默克密理博,AB5430P,Anti-Per3 Antibody

  • 产品介绍
  • merck millipore,默克密理博,AB5430P,Anti-Per3 Antibody

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    MWB, ELISARbAffinity PurifiedPolyclonal Antibody
    描述
    产品目录编号 AB5430P
    品牌系列 Chemicon®
    商名
    • Chemicon
    描述 Anti-Per3 Antibody
    Alternate Names
    • Period Circadian Protein 3
    产品信息
    格式 Affinity Purified
    演示 Affinity purified immunoglobulin. Liquid in PBS, containing 0.1% BSA .
    应用
    应用 Anti-Per3 Antibody is an antibody against Per3 for use in ELISA & WB.
    主要应用
    • Western Blotting
    • ELISA
    应用说明 Western blot: 1-10 μg/mL using ECL.

    ELISA: 1:10,000-1:100,000 using 50-100 ng control peptide per well.

    Optimal working dilutions must be determined by the end user.
    生物信息
    免疫原品种 A 20 amino acid peptide sequence within the C-teriminus of mouse Per 3 (Zylka, 1998).
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Rabbit
    特异性 Recognizes mouse Per 3. . Reactivity with other species has not been confirmed. The immunogen sequence shows 77% homology with mouse Per3 and 50% with human and drosophila.
    品种反应性 Mouse
    抗体类型 Polyclonal Antibody
    Entrez基因编号
    • NM_016831.1
    Entrez基因汇总 This gene is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior. Circadian expression in the suprachiasmatic nucleus continues in constant darkness, and a shift in the light/dark cycle evokes a proportional shift of gene expression in the suprachiasmatic nucleus. The specific function of this gene is not yet known.
    基因符号
    • ORFNames=GIG13
    • PER3
    • hPER3
    • GIG13
    UniProt编号
    • P56645
    UniProt汇总 FUNCTION: SwissProt: P56645 # Component of the circadian clock mechanism which is essential for generating circadian rhythms. Function unknown.
    SIZE: 1201 amino acids; 131872 Da
    SUBUNIT: Homodimer. Component of the circadian core oscillator, which includes the CRY proteins, CLOCK or NPAS2, BMAL1 or BMAL2, CSNK1D and/or CSNK1E, TIMELESS and the PER proteins. Interacts directly with PER1, PER2, CRY1, CRY2, and TIMELESS. Interaction with CSNK1D or CSKN1E promotes nuclear location of PER proteins (By similarity).
    SUBCELLULAR LOCATION: Cytoplasm (By similarity). Nucleus (By similarity). Note=Mainly cytoplasmic. Translocates to the nucleus through binding PER1, PER2, CRY1 or CRY2, but not TIMELESS (By similarity).
    PTM: Phosphorylation appears to require association with PER1 and translocation to the nucleus (By similarity). & Ubiquitinated (By similarity).
    SIMILARITY: SwissProt: P56645 ## Contains 1 PAC (PAS-associated C-terminal) domain. & Contains 2 PAS (PER-ARNT-SIM) domains.
    产品使用声明
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Maintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles.
    包装信息
    数量 50 µg

    merck millipore,默克密理博,AB5430P,Anti-Per3 Antibody

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