merck millipore,默克密理愽
  • merck millipore,默克密理博,AB5425,Anti-Tyrosine Hydroxylase Antibody, phosphoSer19

  • merck millipore,默克密理博,AB5425,Anti-Tyrosine Hydroxylase Antibody, phosphoSer19

    产品名称：Anti-Tyrosine Hydroxylase Antibody, phosphoSer19
    产品型号：AB5425
    Anti-Tyrosine Hydroxylase Antibody, phosphoSer19 is an antibody against Tyrosine Hydroxylase for use in IC, IH & WB.

    merck millipore,默克密理博,AB5425,Anti-Tyrosine Hydroxylase Antibody, phosphoSer19

  • 产品介绍
  • merck millipore,默克密理博,AB5425,Anti-Tyrosine Hydroxylase Antibody, phosphoSer19

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    RWB, ICC, IHCRbAffinity PurifiedPolyclonal Antibody
    描述
    产品目录编号 AB5425
    品牌系列 Chemicon®
    商名
    • Chemicon
    描述 Anti-Tyrosine Hydroxylase Antibody, phosphoSer19
    产品信息
    格式 Affinity Purified
    演示 Affinity purified immunoglobulin. Each vial contains approximately 10 mg of affinity-purified antibody in 100 μL of 10 mM HEPES (pH 7.5), 150 mM NaCl, 0.1 mg/mL BSA and 50% glycerol.
    应用
    应用 Anti-Tyrosine Hydroxylase Antibody, phosphoSer19 is an antibody against Tyrosine Hydroxylase for use in IC, IH & WB.
    主要应用
    • Western Blotting
    • Immunocytochemistry
    • Immunohistochemistry
    应用说明 Western blot: 1:1,000

    Immunocytochemistry: 1:1,000

    Immunohistochemistry: 1:1,000

    Optimal working dilutions must be determined by the end user.
    生物信息
    免疫原品种 Synthetic peptide from the phosphoSer19 of rat Tyrosine Hydroxylase.
    表位 phosphoSer19
    宿主 Rabbit
    特异性 Tyrosine Hydroxylase, phosphoSer19. The antibody recognizes a protein of 60 kDa corresponding to TH phosphorylated at Ser19 in lysates of PC-12 cells stimulated by okadaic acid. Depending upon the brain region being studied, protein load and detection methods some higher molecular weight bands may be detected.
    品种反应性 Rat
    抗体类型 Polyclonal Antibody
    Entrez基因编号
    • NM_199293.2
    • NM_000360.3
    • NM_199292.2
    Entrez基因汇总 Tyrosine hydroxylase is involved in the conversion of tyrosine to dopamine. As the rate-limiting enzyme in the synthesis of catecholamines, tyrosine hydroxylase has a key role in the physiology of adrenergic neurons.
    基因符号
    • TYH
    • EC 1.14.16.2
    • TH
    修改
    • Phosphorylation
    UniProt编号
    • P07101
    UniProt汇总 FUNCTION: SwissProt: P07101 # Plays an important role in the physiology of adrenergic neurons.
    COFACTOR: Fe(2+) ion.
    SIZE: 528 amino acids; 58524 Da
    TISSUE SPECIFICITY: Mainly expressed in the brain and adrenal glands.
    DISEASE: SwissProt: P07101 # Defects in TH are the cause of autosomal recessive Segawa syndrome [MIM:605407]; also known as DOPA-responsive dystonia. Typically, it begins in childhood or adolescence with progressive difficulty in walking and, in some cases, spasticity. Some cases present with parkinsonian symptoms in infancy and are referred to as autosomal recessive infantile parkinsonism.
    SIMILARITY: SwissProt: P07101 ## Belongs to the biopterin-dependent aromatic amino acid hydroxylase family.
    产品使用声明
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Maintain at -20°C in undiluted for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles. Do not store in a self-defrosting freezer.
    包装信息
    数量 100 µL

    merck millipore,默克密理博,AB5425,Anti-Tyrosine Hydroxylase Antibody, phosphoSer19

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