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描述 概述 Full-length, recombinant, human, lipocortin-II fused at the N-terminus to His•Tag® and S•Tag™ sequences and expressed in E. coli. This preparation is qualified for use as a substrate for protein tyrosine kinases in in vitro assays. Lipocortin-II is a Ca2+-binding protein whose affinity for calcium is increased by anionic phospholipids. It binds two calcium ions with high-affinity and crosslinks plasma membrane phospholipids with actin and the cytoskeleton and is involved with exocytosis. It is known to be phosphorylated at Tyr23 by Src and at Ser25 by PKC. It is also a substrate for a variety of other protein tyrosine kinases. 产品目录编号 437622 品牌系列 Calbiochem®
同义词 Annexin-II, Human, Recombinant, Calpactin-I, Human, Recombinant, Lipocortin-II, Human, Recombinant 应用数据 
参考 参考 Deora, A.B., et al. 2004. J. Biol. Chem. 279, 43411.
Lennon, G., et al. 1996. Genomics 33, 151.
Barton, G. J., et al. 1991. Eur. J. Biochem. 198, 749.产品信息 形式 Liquid 配方 In PBS, 0.2% Protease Inhibitor Cocktail Set VII (Cat. No. 539138). Molar Mass 43400 生物信息 纯度 ≥90% by SDS-PAGE 浓缩标签 Please refer to vial label for lot-specific concentration
储存和货运信息 货运代码 Dry Ice Only
毒性 Irritant
储存 ≤ -70°C
避免冻结 / 解冻 Avoid freeze/thaw
无需冷冻 No
特殊指南 Following initial thaw, aliquot and freeze (-70°C).
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