merck millipore,默克密理愽
  • merck millipore,默克密理博,AB5358-200UL,Anti-Sodium Channel NaB2 Antibody

  • merck millipore,默克密理博,AB5358-200UL,Anti-Sodium Channel NaB2 Antibody

    产品名称：Anti-Sodium Channel NaB2 Antibody
    产品型号：AB5358-200UL
    Anti-Sodium Channel NaB2 Antibody detects level of Sodium Channel NaB2 & has been published & validated for use in IH & WB.

    merck millipore,默克密理博,AB5358-200UL,Anti-Sodium Channel NaB2 Antibody

  • 产品介绍
  • merck millipore,默克密理博,AB5358-200UL,Anti-Sodium Channel NaB2 Antibody

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    RWB, IHCRbAffinity PurifiedPolyclonal Antibody
    描述
    产品目录编号 AB5358-200UL
    品牌系列 Chemicon®
    商名
    • Chemicon
    描述 Anti-Sodium Channel NaB2 Antibody
    Alternate Names
    • SCN2B
    • B2 Subunit of Voltage-Gated Na+ Channel
    产品信息
    格式 Affinity Purified
    控制
    • CONTROL ANTIGEN: Included free of charge with the antibody is 20 μg of control antigen (lyophilized powder). For negative control, preincubate 1 μg of purified peptide with 1 μg of antibody for one hour at room temperature. Optimal concentrations must be determined by the end user.
    演示 Affinity purified immunoglobulin. Lyophilized from PBS, pH 7.4, containing 1% BSA, and 0.05 % sodium azide. Reconstitute with 200 μL of sterile distilled water. Centrifuge antibody preparation before use (10,000 x g for 5 min).
    应用
    应用 Anti-Sodium Channel NaB2 Antibody detects level of Sodium Channel NaB2 & has been published & validated for use in IH & WB.
    主要应用
    • Western Blotting
    • Immunohistochemistry
    应用说明 Western blotting: 1:200 on rat brain membranes.

    Immunohistochemistry on rat brain sections.

    Dilutions should be made using a carrier protein such as BSA (1-3%).

    Optimal working dilutions must be determined by the end user.
    生物信息
    免疫原品种 Highly purified peptide corresponding to residues 197-215 of rat beta2 subunit of voltage-gated Na+ channels (Isom et al. 1995). Accession P54900. It is expected to work on human because the immunogen sequence is highly conserved (17/19 residues). Reactivity with other species has not yet been tested.
    浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration.
    宿主 Rabbit
    特异性 Recognizes Nab2. The epitope specific for Nab2 is not present in any other known proteins.
    品种反应性 Rat
    抗体类型 Polyclonal Antibody
    Entrez基因编号
    • NM_004588.3
    基因符号
    • ORFNames=UNQ326/PRO386
    • SCN2B
    UniProt编号
    • O60939
    UniProt汇总 FUNCTION: SwissProt: O60939 # Crucial in the assembly, expression, and functional modulation of the heterotrimeric complex of the sodium channel. The subunit beta-2 causes an increase in the plasma membrane surface area and in its folding into microvilli. Interacts with TNR may play a crucial role in clustering and regulation of activity of sodium channels at nodes of Ranvier (By similarity).
    SIZE: 215 amino acids; 24326 Da
    SUBUNIT: The sodium channel consists of a pore-forming alpha subunit, beta-1 and beta-2 subunits. Beta-1 is non-covalently associated with alpha, while beta-2 is covalently linked by disulfide bonds. Interaction with SCN10A and TNR (By similarity).
    SUBCELLULAR LOCATION: Membrane; Single-pass type I membrane protein.
    TISSUE SPECIFICITY: Brain specific.
    SIMILARITY: SwissProt: O60939 ## Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
    产品使用声明
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Maintain lyophilized material at -20°C for up to 6 months. After reconstitution maintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles.
    包装信息
    数量 200 µL

    merck millipore,默克密理博,AB5358-200UL,Anti-Sodium Channel NaB2 Antibody

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