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品种反应性 主要应用 宿主 抗体类型 R, H, M WB Rb Polyclonal Antibody 描述 产品目录编号 AB1094 描述 Anti-Myosin X Antibody Alternate Names - Unconventional myosin-10
- Unconventionnal myosin-X
背景信息 Myosins are a superfamily of molecular motor proteins found in eukaryotic cells. Motor proteins are involved in muscular contraction, cytokinesis, short-range membrane/vesicle transport and a host of other cellular processes. The myosins are responsible for actin-based motility by using the energy of ATP hydrolysis to generate force and movement along actin filaments. There are many isoforms of myosin of which some have specialized functions in certain cell types (such as muscle), while other isoforms are ubiquitous. Myosin X belongs to a group of myosin isoforms known as unconventional myosins that participate in cellular processes ranging from membrane trafficking to signaling and cell motility. Myosin X is concentrated at the tips of filopodia and Myosin X rich regions travel forward and backward along filopods, (Berg, 2002). It also appears that Myosin X functions in actual filopodia formation, (Bohil, 2006). 产品信息 控制 - Human head/neck lysate.
演示 Rabbit serum containing 0.05% NaN3. 应用 应用 Detect Myosin X using this Anti-Myosin X Antibody validated for use in WB. 主要应用 - Western Blotting
生物信息 免疫原品种 KLH-conjugated synthetic peptide to amino acids 936-953 of human Myosin X. 表位 a.a. 936-953 宿主 Rabbit 特异性 Cat. No. AB1094 recognizes human Myosin X. 品种反应性 RatHumanMouse Species Reactivity Note Human. Predicted to cross react with mouse and rat based on 100% sequence homology. Reactivity with other species has not been tested. 抗体类型 Polyclonal Antibody Entrez基因编号 - AAF37875
基因符号 - MYO10
UniProt编号 - Q9HD67
UniProt汇总 FUNCTION: Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements. Their highly divergent tails are presumed to bind to membranous compartments, which would be moved relative to actin filaments. Plays a role in regions of dynamic actin.
SUBUNIT STRUCTURE: Interacts with ECM29.
CAUTION: Represents a unconventional myosin. This protein should not be confused with the conventional myosin-10 (MYH10).
SIZE: 237 kDa产品使用声明 质量保证 Evaluated on a representative lot by Western blot on human head/neck lysate using Anti-Myosin X. 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Maintain at -20°C for up to 1 year from date of receipt.
Upon arrival, aliquot into usable quantities to avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
包装信息 数量 100 µL
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