merck millipore,默克密理愽
  • merck millipore,默克密理博,AB3241-25UL,Anti-Cdc2 Antibody, phospho-specific (Tyr15)

  • merck millipore,默克密理博,AB3241-25UL,Anti-Cdc2 Antibody, phospho-specific (Tyr15)

    产品名称：Anti-Cdc2 Antibody, phospho-specific (Tyr15)
    产品型号：AB3241-25UL
    Use Anti-Cdc2 Antibody, phospho-specific (Tyr15) (Rabbit Polyclonal Antibody) validated in WB to detect Cdc2 also known as Cell Division Cycle 2, p34 Protein Kinase.

    merck millipore,默克密理博,AB3241-25UL,Anti-Cdc2 Antibody, phospho-specific (Tyr15)

  • 产品介绍
  • merck millipore,默克密理博,AB3241-25UL,Anti-Cdc2 Antibody, phospho-specific (Tyr15)

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    RWBRbAffinity PurifiedPolyclonal Antibody
    描述
    产品目录编号 AB3241-25UL
    品牌系列 Chemicon®
    商名
    • Chemicon
    描述 Anti-Cdc2 Antibody, phospho-specific (Tyr15)
    Alternate Names
    • Cyclin-dependent Kinase 1
    • Cell Division Cycle 2
    • p34 Protein Kinase
    产品信息
    格式 Affinity Purified
    演示 Affinity purified immunoglobulin in 10 mM Hepes, pH 7.5, with 150 mM NaCl, 100 μg/mL BSA and 50% glycerol.
    应用
    应用 Use Anti-Cdc2 Antibody, phospho-specific (Tyr15) (Rabbit Polyclonal Antibody) validated in WB to detect Cdc2 also known as Cell Division Cycle 2, p34 Protein Kinase.
    主要应用
    • Western Blotting
    应用说明 Western blot: 1:1,000

    Optimal working dilutions must be determined by the end user.
    生物信息
    免疫原品种 Synthetic peptide corresponding to amino acids surrounding the phosphoTry15 of human, rat, mouse and Xenopus CDC2.
    表位 phospho-specific (Tyr15)
    宿主 Rabbit
    特异性 CDC2, phosphoTyr15. By Western blot the antibody recognizes the ~35 kDa phospho CDC2 protein. The labeling of the CDC2 band in Western blots of rat brain is blocked by the phosphopeptide but not by the dephosphopeptide.
    品种反应性 Rat
    抗体类型 Polyclonal Antibody
    Entrez基因编号
    • NM_033379.2
    • NM_001786.2
    Entrez基因汇总 The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control.
    基因符号
    • EC 2.7.11.23
    • CDC2
    • CDK1
    • DKFZp686L20222
    • MGC111195
    • CDC28A
    • EC 2.7.11.22
    修改
    • Phosphorylation
    UniProt编号
    • P06493
    UniProt汇总 FUNCTION: SwissProt: P06493 # Plays a key role in the control of the eukaryotic cell cycle. It is required in higher cells for entry into S-phase and mitosis. p34 is a component of the kinase complex that phosphorylates the repetitive C-terminus of RNA polymerase II.
    SIZE: 297 amino acids; 34095 Da
    SUBUNIT: Forms a stable but non-covalent complex with a regulatory subunit and with a cyclin. Interacts with DLG7. Isoform 2 is unable to complex with cyclin B1 and also fails to bind to the CDK inhibitor p21. Interacts with catalytically active CCNB1 and RALBP1 during mitosis to form an endocytotic complex during interphase.
    SUBCELLULAR LOCATION: Nucleus (By similarity).
    SIMILARITY: SwissProt: P06493 ## Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily. & Contains 1 protein kinase domain.
    产品使用声明
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Maintain at -20°C in undiluted for up to 6 months from date of receipt. Avoid repeated freeze/thaw cycles. Do not store in a self-defrosting freezer.
    包装信息
    数量 25 µL

    merck millipore,默克密理博,AB3241-25UL,Anti-Cdc2 Antibody, phospho-specific (Tyr15)

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下一件merck millipore产品：merck millipore,默克密理博,SF-1215,PARK2; Rat, Cyanine 5 RNA Detection Probe,SmartFlare


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