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经验配方 CAS号 C₁₄H₁₁N₃O₃S 31430-18-9 描述 概述 Inhibitor of mitosis. Has highly specific antimicrotubular activity for mammalian cells in culture. Promotes tubulin depolymerization. Also available as a 50 mM solution in DMSO (Cat. No. 487929). 产品目录编号 487928 品牌系列 Calbiochem®
同义词 R17934, Methyl-[5-(2-thienylcarbonyl)-1H-benzimidazol-2-yl]-carbamate 参考 参考 Park, H., et al. 2011. Chem. Med. Chem. in press.
Bunz, F., et al. 1998. Science 282, 1497.
Fleischman, L.F., et al. 1993. Oncogene 8, 771.
Pomies, P., and Block, M.R. 1992. Biochem. Biophys. Res. Commun. 189, 1429.
Rennison, M.E., et al. 1992. J. Cell Sci. 102, 239.
Thyberg, J., and Moskalewski, S. 1992. J. Cell Sci. 103, 1167.产品信息 CAS号 31430-18-9 具有ATP竞争性 N 形式 Pale yellow solid Hill配方 C₁₄H₁₁N₃O₃S 化学配方 C₁₄H₁₁N₃O₃S Molar Mass 301.3 可逆 N 结构配方图像 生物信息 主靶 Promotes tubulin depolymerization 纯度 ≥99% by HPLC 理化信息 细胞可渗透 N 溶解度 DMSO GHS安全信息 RTECS DD6521000 安全信息 R相 R: 40-63
Limited evidence of a carcinogenic effect.
Possible risk of harm to the unborn child.S相 S: 36
Wear suitable protective clothing.储存和货运信息 货运代码 Ambient Temperature Only
毒性 Carcinogenic / Teratogenic
储存 +15°C to +30°C
无需冷冻 No
特殊指南 Following reconstitution, aliquot and freeze (-20°C) for long-term storage or refrigerate (4°C) for short-term storage. Stock solutions are stable for up to 1 week at 4°C or for up to 1 year at -20°C.
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