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品种反应性 主要应用 宿主 格式 抗体类型 R WB, ELISA Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 AB3085 品牌系列 Chemicon®
商名 - Chemicon
描述 Anti-Na+/H+ Exchanger-3 Antibody Alternate Names - NHE3
产品信息 格式 Affinity Purified 控制 - Kidney, jejunum, colon, and stomach tissue
演示 Affinity Purified immunoglobulin. Liquid in PBS with 0.1% BSA. 应用 应用 This Anti-Na+/H+ Exchanger-3 Antibody is validated for use in ELISA, WB for the detection of Na+/H+ Exchanger-3. 主要应用 - Western Blotting
- ELISA
应用说明 Western blot: 1-10 μg/mL using Chemiluminescence technique. A band of approximately 90 kD has been detected in brush border membrane (Yohsioka et al. 1997). ELISA: 1:100,000 using 50-100 ng control peptide/well.
Optimal working dilutions must be determined by end user.生物信息 免疫原品种 A 22 AA peptide within the cytoplasmic, c-terminal domain of the rat NHE3 (Brant et al. 1995; Orlowsji et al. 1992; Chris Yun et al. 1995; Josette & Pouyssegur 1995). Control peptide is available, cat# AG779. 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 特异性 Recognizes NHE3. 品种反应性 Rat Species Reactivity Note The immunogen sequence shares 90% homology with mouse NHE3. 抗体类型 Polyclonal Antibody Entrez基因编号 - NP_004165
基因符号 - MGC126718
- SLC9A3
- Na
- NHE3
- MGC126720
- NHE-3
- +H
纯化方法 Immunoaffinity purified UniProt编号 - P48764
UniProt汇总 FUNCTION: SwissProt: P48764 # Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Plays an important role in signal transduction.
SIZE: 834 amino acids; 92908 Da
SUBUNIT: Binds SLC9A3R1 and SLC9A3R2. Interacts with SHANK2 (By similarity).
SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.
PTM: Phosphorylated by PKA, which inhibits activity (By similarity).
SIMILARITY: SwissProt: P48764 ## Belongs to the Na(+)/H(+) exchanger (TC 2.A.36.5.1) family.产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Maintain for 6 months at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. 包装信息 数量 50 µg
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