merck millipore,默克密理愽
  • merck millipore,默克密理博,AB1592P,Anti-NMDAR2C Antibody, also recognizes NMDAR2A and 2B

  • merck millipore,默克密理博,AB1592P,Anti-NMDAR2C Antibody, also recognizes NMDAR2A and 2B

    产品名称：Anti-NMDAR2C Antibody, also recognizes NMDAR2A and 2B
    产品型号：AB1592P
    Detect NMDAR2C using this Anti-NMDAR2C Antibody, also recognizes NMDAR2A & 2B validated for use in IP & WB.

    merck millipore,默克密理博,AB1592P,Anti-NMDAR2C Antibody, also recognizes NMDAR2A and 2B

  • 产品介绍
  • merck millipore,默克密理博,AB1592P,Anti-NMDAR2C Antibody, also recognizes NMDAR2A and 2B

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    RWBRbAffinity PurifiedPolyclonal Antibody
    描述
    产品目录编号 AB1592P
    品牌系列 Chemicon®
    商名
    • Chemicon
    描述 Anti-NMDAR2C Antibody, also recognizes NMDAR2A and 2B
    产品信息
    格式 Affinity Purified
    演示 Affinity purified immunoglobulin. Lyophilized from ammonium bicarbonate (5 mM), some residual salt may be present. Reconstitute with 50 μL of PBS.
    应用
    应用 Detect NMDAR2C using this Anti-NMDAR2C Antibody, also recognizes NMDAR2A & 2B validated for use in IP & WB.
    主要应用
    • Western Blotting
    不建议的应用
    • Immunohistochemistry
    应用说明 Western blotting 1:100-1:200

    Immunoprecipitation: 3 μL will (under the appropriate conditions) quantitatively immunoprecipitate all NMDAR2C in 200 μg of rat cerebellum.

    Not recommended for use in immunohistochemistry since the antibody also reacts with NMDAR2A and NMDAR2B.

    Optimal working dilutions must be determined by the end user.
    生物信息
    免疫原品种 N-Terminal Fusion Protein of the NMDAR2C
    表位 N-terminus
    宿主 Rabbit
    特异性 NMDAR2C. Immunolabels the 140 kD NMDAR2C subunit of the NMDA receptor. Also reacts with NMDAR2A and NMDAR2B by Western blot (180 kD).
    品种反应性 Rat
    抗体类型 Polyclonal Antibody
    Entrez基因编号
    • NM_000835.3
    Entrez基因汇总 N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. NMDA channel has been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of the key receptor subunit NMDAR1 (GRIN1) and 1 or more of the 4 NMDAR2 subunits: NMDAR2A (GRIN2A), NMDAR2B (GRIN2B), NMDAR2C (GRIN2C), and NMDAR2D (GRIN2D).
    基因符号
    • NMDAR2C
    • GRIN2C
    • Glutamate
    • NR2C
    UniProt编号
    • Q14957
    UniProt汇总 FUNCTION: SwissProt: Q14957 # NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine.
    SIZE: 1233 amino acids; 134240 Da
    SUBUNIT: Interacts with PDZ domains of INADL and DLG4 (By similarity). Forms heteromeric channel of a zeta subunit (GRIN1), a epsilon subunit (GRIN2A, GRIN2B, GRIN2C or GRIN2D) and a third subunit (GRIN3A or GRIN3B).
    SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.
    TISSUE SPECIFICITY: Mainly in brain with predominant expression is in the cerebellum, also present in the hippocampus, amygdala, caudate nucleus, corpus callosum, subthalamic nuclei and thalamus. Detected in the heart, skeletal muscle and pancreas.
    SIMILARITY: SwissProt: Q14957 ## Belongs to the glutamate-gated ion channel (TC 1.A.10) family.
    产品使用声明
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Maintain lyophilized antibody at -20°C for up to 12 months after date of receipt. After reconstitution maintain at -20°C in undiluted aliquots for up to six months.

    Avoid repeated freeze/thaw cycles.
    包装信息
    数量 10 µg

    merck millipore,默克密理博,AB1592P,Anti-NMDAR2C Antibody, also recognizes NMDAR2A and 2B

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下一件merck millipore产品：merck millipore,默克密理博,EZRMGIP-55K,Rat/Mouse GIP (total) ELISA


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