merck millipore,默克密理博,AB15708A4,Anti-Beta III Tubulin Antibody, Alexa Fluor 488 Conjugate,AB15708A4

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Merck Millipore 默克密理愽

merck millipore,默克密理博,AB15708A4,Anti-Beta III Tubulin Antibody, Alexa Fluor 488 Conjugate,AB15708A4
产品名称：Anti-Beta III Tubulin Antibody, Alexa Fluor 488 Conjugate, AB15708A4
产品型号：AB15708A4

merck millipore,默克密理博,AB15708A4,Anti-Beta III Tubulin Antibody, Alexa Fluor 488 Conjugate,AB15708A4

品种反应性	主要应用	宿主	格式	抗体类型
H, R, M	IHC, ICC	Rb	AlexaFluor®488	Polyclonal Antibody

描述
产品目录编号	AB15708A4
描述	Anti-Beta III Tubulin Antibody, Alexa Fluor® 488 Conjugate \| AB15708A4
Alternate Names	tubulin, beta, 4 Tubulin beta-4 Tubulin beta-III tubulin, beta 3
背景信息	Tubulin is one of several members of a small family of globular proteins which polymerize to form cytoskeletal structures called microtubules. The most common members of the tubulin family are α-tubulin and β-tubulin. Tubulin dimers, typically composed of α- and β-tubulin subunits, assemble onto microtubules forming large polymers. β-III tubulin is a unique microtubule subunit that is found expressed almost exclusively in neurons. Due to the unique expression pattern of β-III tubulin it is often utilized as a marker to identify neuronal cells from other brain cells such as glia which do not express it. β-III tubulin also serves as a cytoarchitectural marker since it is primarily found within neurite extensions.

产品信息
格式	AlexaFluor®488
控制	Rat E18 cortex cells
演示	Purified rabbit polyclonal conjugated to Alexa Fluor® 488 in PBS with 0.1% sodium azide and 15 mg/mL BSA.

应用
主要应用	Immunohistochemistry Immunocytochemistry
应用说明	Immunohistochemistry: Representive lot has been shown to work in adult mouse brain.

生物信息
免疫原品种	Synthetic linear peptide corresponding to human Beta III Tubulin.
宿主	Rabbit
特异性	This antibody recognizes Beta III Tubulin.
品种反应性	HumanRatMouse
Species Reactivity Note	Demonstrated to react with Rat and Mouse. Predicted to react with Human based on 100% sequence homology.
抗体类型	Polyclonal Antibody
Entrez基因编号	NP_006077
Entrez基因汇总	This gene encodes a class III member of the beta tubulin protein family. Beta tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules. This protein is primarily expressed in neurons and may be involved in neurogenesis and axon guidance and maintenance. Mutations in this gene are the cause of congenital fibrosis of the extraocular muscles type 3. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 6.
基因符号	beta-4 TUBB3 TUBB4 MC1R
纯化方法	Affinity purified
UniProt编号	Q13509
UniProt汇总	FUNCTION: Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain. SIZE: 450 amino acids; 50433 Da SUBUNIT: Dimer of alpha and beta chains. DOMAIN: The highly acidic C-terminal region may bind cations such as calcium. SIMILARITY: Belongs to the tubulin family.

产品使用声明
质量保证	Evaluated by Immunocytochemistry in rat E18 cortex cells. Immunocytochemistry Analysis: A 1:400 dilution of this antibody detected Beta III Tubulin in rat E18 cortex cells.
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Stable for 1 year at 2-8°C from date of receipt.

包装信息
数量	100 µL

merck millipore,默克密理博,AB15708A4,Anti-Beta III Tubulin Antibody, Alexa Fluor 488 Conjugate,AB15708A4

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