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品种反应性 主要应用 宿主 格式 抗体类型 H, M IHC, WB R Purified Monoclonal Antibody 描述 产品目录编号 05-1573 Replaces MABE517 描述 Anti-Pax5 Antibody, clone 1H9 Alternate Names - BSAP
- Paired box protein Pax-5
- B-cell-specific transcription factor
背景信息 Pax5, also known as B-cell-specific transcription factor (BASP), and encoded by the gene Pax5/Pax-5, plays a role in B cell differentiation and neural development and spermatogenesis. Pax5 regulates the expression of CD19 a B lymphoid specific target gene. Additionally, Pax5 interacts with ETS1 and alters its DNA binding abilities and it interacts with DAXX and TLE4. Pax5 is localized to the nucleus. Pax5 is expressed at early B-cell differentiation and in the developing CNS during development. In the adult it is expressed in the testis. Pax5 is also involved in B-cell related diseases and lymphomas and most recently was shown to be the controlling factor of the “Z” protein BZLF1 which controls the latent to lytic switch of Epstein-Barr virus (EBV) in humans. 产品信息 格式 Purified 演示 Purified rat monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide. 应用 应用 Detect PAX5 using this rat monoclonal antibody, Anti-Pax5 Antibody, clone 1H9 validated for use in western blotting & IHC. 主要应用 - Immunohistochemistry
- Western Blotting
应用说明 Western Blotting Analysis: 0.5 µg/mL from a representative lot detected Pax5 in 10 µg of mouse E13-E14 brain tissue lysate.
Immunohistochemistry Analysis: A 1:2,000 dilution from a representative lot detected Isocitrate dehydrogenase in human tonsil and mouse hindbrain tissue.生物信息 免疫原品种 GST-tagged recombinant protein corresponding to mouse Pax5. 克隆 1H9 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rat 同种型 IgG2aκ 品种反应性 HumanMouse 抗体类型 Monoclonal Antibody Entrez基因编号 - NP_032808
基因符号 - Pax-5
- Pax5
纯化方法 Protein G purified UniProt编号 - Q02650
产品使用声明 质量保证 Evaluated by Western Blotting in Ramos cell lysate.
Western Blotting Analysis: 0.5 µg/mL of this antibody detected Pax5 in 10 µg of Ramos cell lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Stable for 1 year at 2-8°C from date of receipt. 包装信息 数量 100 µg
上一件merck millipore产品：merck millipore,默克密理博,MAB319,Anti-Chromogranin A Antibody, clone PHE5
下一件merck millipore产品：merck millipore,默克密理博,CBL147,Anti-BL-CAM Antibody, clone RFB4
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