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品种反应性 主要应用 宿主 格式 抗体类型 M, R WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 AB15858 品牌系列 Chemicon®
商名 - Chemicon
描述 Anti-Aquaporin 5 Antibody Alternate Names - AQP5
背景信息 Aquaporins (AQPs) are a family of channel proteins that allow water or very small solutes to pass, functioning in tissues where the rapid and regulated transport of fluid is necessary, such as the kidney, lung, and salivary glands. Aquaporin 5 is considered to play an important role in water movement across the plasma membrane in salivary fluid secretion and corneal/lens lubrication and is a focus of studies illucidating bechanisms underlying diabetic xerostomia. 产品信息 格式 Affinity Purified 控制 - Tested on Rat Salivary Gland Lysate
演示 Purified rabbit polyclonal in buffer containing PBS with 0.05% sodium azide. 应用 应用 This Anti-Aquaporin 5 (AQP5) Antibody is validated for use in WB for the detection of Aquaporin 5 (AQP5). 主要应用 - Western Blotting
应用说明 Immunohistochemistry Analysis: A 1:500-2,000 dilution from a representative lot detected Aquaporin 5 in rat lung and mouse trachea tissue.
Immunohistochemistry Analysis: A representative lot from independent laboratories detected Aquaporin 5 in various paraformaldehyde fixed tissues (see references).生物信息 免疫原品种 KLH-conjugated linear peptide corresponding to the cytoplasmic domain of rat Aquaporin 5. 表位 Cytoplasmic domain 浓缩 1 mg/mL 宿主 Rabbit 特异性 Aquaporin 5 (AQP5). By Western blot the antibody reacts with a band at ~ 24 kDa on rat submaxillary gland lysate. 品种反应性 MouseRat 抗体类型 Polyclonal Antibody Entrez基因编号 - NP_036911
Entrez基因汇总 Aquaporin 5 (AQP5) is a water channel protein. Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein (MIP or AQP0). Aquaporin 5 plays a role in the generation of saliva, tears and pulmonary secretions. AQP0, AQP2, AQP5, and AQP6 are closely related and all map to 12q13. 基因符号 - Aquaporin-5
- AQP5
- AQP-5
纯化方法 Immunoaffinity purified UniProt编号 - P47864
UniProt汇总 FUNCTION: SwissProt: P55064 # Forms a water-specific channel. Implicated in the generation of saliva, tears, and pulmonary secretions.
SIZE: 265 amino acids; 28292 Da
SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.
DOMAIN: SwissProt: P55064 Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).
SIMILARITY: Belongs to the MIP/aquaporin (TC 1.A.8) family.产品使用声明 质量保证 Evaluated by Western Blotting in rat salivary gland tissue lysate.
Western Blotting Analysis: 0.1 µg/mL of this antibody detected Aquaporin 5 in 10 µg of rat salivary gland tissue lysate.使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Maintain at 2-8°C in undiluted aliquots for up to 1 year after date of receipt.
During shipment, small volumes of product will occasionally become entrapped in the seal of the product vial. For products with volumes of 200μL or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container's cap.包装信息 数量 100 µg
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