merck millipore,默克密理愽
  • merck millipore,默克密理博,14-922,TrkC, active

  • merck millipore,默克密理博,14-922,TrkC, active

    产品名称：TrkC, active
    产品型号：14-922


    merck millipore,默克密理博,14-922,TrkC, active

  • 产品介绍
  • merck millipore,默克密理博,14-922,TrkC, active

    描述
    产品目录编号 14-922
    商名
    • Upstate
    描述 TrkC, active
    概述 TrkC is a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation and may play a role in the development of proprioceptive neurons that sense
    body position. Mutations in this gene have been associated with medulloblastomas, secretory breast carcinomas and other cancers. Several transcript variants encoding different isoforms have been found for this gene.
    产品信息
    演示 50mM Tris/HCl pH7.5, 300mM NaCl, 0.1mM EGTA, 0.03% Brij-35, 270mM sucrose, 1mM benzamidine, 0.2mM PMSF, 0.1% 2-mercaptoethanol
    应用
    主要应用
    • Kinase Assay
    生物信息
    来源 N-terminal GST-tagged and C-terminal 6His-tagged, recombinant, human TrkC amino acids 510-end, expressed by baculovirus in Sf21 insect cells
    品种 Human
    特异活性 For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.
    Entrez基因编号
    • NM_002530
    基因符号
    • Trk-C
    • TRKC
    • NTRK3
    纯化方法 Purified using glutathione agarose followed by gel filtration.
    靶子系列 TK
    UniProt编号
    • Q16288
    产品使用声明
    质量保证 Routinely evaluated by phosphorylation of GEEPLYWSFPAKKK
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 6 months at -70°C
    包装信息
    数量 10 µg
    包装 Also available in 250μg size as catalog # 14-922M and in bulk as catalog # 14-922-K.

    merck millipore,默克密理博,14-922,TrkC, active

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