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描述 产品目录编号 14-910M 品牌系列 Upstate
商名 - Upstate
描述 PI3K-C2γ Protein, 250 µg 概述 N-terminal GST-tagged recombinant human PI3K-C2γ amino acids 468–1203 产品信息 演示 0.54mg/ml of enzyme in 50mM Tris/HCl pH7.5, 300mM NaCl, 0.1mM EGTA, 0.03% Brij-35, 270mM sucrose, 0.2mM PMSF, 1mM benzamidine, 0.1% 2-mercaptoethanol. Frozen solution. 应用 应用 N-terminal GST-tagged recombinant human PI3K-C2γ, amino acids 468–1203, for use in Kinase Assays. 主要应用 - Kinase Assay
生物信息 来源 Expressed by baculovirus in Sf21 insect cells 品种 Human 特异活性 For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme. Entrez基因编号 - BC130277
Entrez基因汇总 The protein encoded by this gene belongs to the phosphoinositide 3-kinase (PI3K) family. PI3-kinases play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. This protein contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases. C2 domains act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions. The biological function of this gene has not yet been determined. 基因符号 - PIK3C2G
- PI3-kinase
- PIK3
- PI3K
- PTDINS-3-kinase
- PI3K C2g
- PI3-Kinase Class II
蛋白靶 PI3K-C2γ 纯化方法 Glutathione agarose affinity chromatography 靶子系列 PI3K/PI4K UniProt编号 - O75747
UniProt汇总 FUNCTION: In vitro, phosphorylates PtdIns and PtdIns4P but not PtdIns(4,5)P2
CATALYTIC ACTIVITY: ATP + 1-phosphatidyl-1D-myo-inositol 4-phosphate = ADP + 1-phosphatidyl-1D-myo-inositol 3,4-bisphosphate.
SUBCELLULAR LOCATION: Membrane; Peripheral membrane protein
TISSUE SPECIFICITY: Highly expressed in liver, prostate and testis. Lower levels in small intestine, kidney and pancreas.
SIMILARITY: Belongs to the PI3/PI4-kinase family. Contains 1 C2 domain. Contains 1 PI3K/PI4K domain. Contains 1 PX (phox homology) domain.产品使用声明 质量保证 Routinely evaluated in the PIProfiler. 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 6 months at -70°C 包装信息 数量 250 µg 包装 Also available in 10 μg size (cat#14-910) and in bulk (cat# 14-910-K).
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下一件merck millipore产品：merck millipore,默克密理博,14-922,TrkC, active
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