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品种反应性 主要应用 宿主 格式 抗体类型 R, Gp, H, M WB, IHC Gt Serum Polyclonal Antibody 描述 产品目录编号 AB1550 品牌系列 Chemicon®
商名 - Chemicon
描述 Anti-Calretinin Antibody 产品信息 格式 Serum 控制 - Rat brain cortex, Mesothelioma tissue
演示 UnPurified goat Serum containing no preservatives. 应用 应用 Detect Calretinin using this Anti-Calretinin Antibody validated for use in IH & WB. 主要应用 - Western Blotting
- Immunohistochemistry
应用说明 Western blot at 1:10,000.
Immunohistochemistry: IFA at 1:2,500, PAP at 1:2,500 (48 hours at +4 C).
Optimal working dilutions must be determined by the end user.生物信息 免疫原品种 Rat calretinin. 浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Goat 特异性 Recognizes Calretinin. 品种反应性 RatGuinea PigHumanMouse 抗体类型 Polyclonal Antibody Entrez基因编号 - NM_007088.2
- NM_001740.3
- NM_007087.2
Entrez基因汇总 Calbindin 2 (calretinin), closely related to calbindin 1, is an intracellular calcium-binding protein belonging to the troponin C superfamily. Calbindin 1 is known to be involved in the vitamin-D-dependent calcium absorption through intestinal and renal epithelia, while the function of neuronal calbindin 1 and calbindin 2 is poorly understood. The sequence of the calbindin 2 cDNA reveals an open reading frame of 271 codons coding for a protein of 31,520 Da, and shares 58% identical residues with human calbindin 1. Calbindin 2 contains five presumably active and one presumably inactive calcium-binding domains. Comparison with the partial sequences available for chick and guinea pig calbindin 2 reveals that the protein is highly conserved in evolution. The calbindin 2 message was detected in the brain, while absent from heart muscle, kidney, liver, lung, spleen, stomach and thyroid gland. There are two additional forms of alternatively spliced calbindin 2 mRNAs encoding C-terminally truncated proteins. Exon 7 can splice to exon 9, resulting in a frame shift and a translational stop at the second codon of exon 9, and encoding calretinin-20k. Exon 7 can also splice to exon 10, resulting in a frame shift and a translational stop at codon 15 of exon 10, and encoding calretinin-22k. The truncated proteins are able to bind calcium. 基因符号 - CAL2
- CALB2
- Calretinin
- CAB29
- CR
纯化方法 Unpurified UniProt编号 - P22676
UniProt汇总 FUNCTION: SwissProt: P22676 # Calretinin is a calcium-binding protein which is abundant in auditory neurons.
SIZE: 271 amino acids; 31540 Da
TISSUE SPECIFICITY: Brain.
SIMILARITY: SwissProt: P22676 ## Belongs to the calbindin family. & Contains 6 EF-hand domains.产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Maintain for 1 year at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. 包装信息 数量 100 µL
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