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品种反应性 主要应用 宿主 格式 抗体类型 H WB Rb Purified Polyclonal Antibody 描述 产品目录编号 AB5785 品牌系列 Chemicon®
商名 - Chemicon
描述 Anti-Calcium Channel β 1 Antibody 产品信息 格式 Purified 演示 Purified immunoglobulin. Liquid in PBS containing 0.08% sodium azide. 应用 应用 Anti-Calcium Channel Antibody, β 1 detects level of Calcium Channel & has been published & validated for use in WB. 主要应用 - Western Blotting
应用说明 Immunoblotting: 5-10 μg/mL
Optimal working dilutions must be determined by the end user.生物信息 免疫原品种 Synthetic peptide from rat beta1 calcium channel.
It is expected that the antibody will work in human and on rat. Other species have not been tested.浓缩 Please refer to the Certificate of Analysis for the lot-specific concentration. 宿主 Rabbit 特异性 beta1 calcium channel (Voltage-Dependant L-type Calcium Channel, beta1 subunit). 品种反应性 Human 抗体类型 Polyclonal Antibody Entrez基因编号 - NM_199248.1
- NM_000723.3
- NM_199247.1
Entrez基因汇总 The protein encoded by this gene belongs to the calcium channel beta subunit family. It plays an important role in the calcium channel by modulating G protein inhibition, increasing peak calcium current, controlling the alpha-1 subunit membrane targeting and shifting the voltage dependence of activation and inactivation. Alternative splicing occurs at this locus and three transcript variants encoding three distinct isoforms have been identified. 基因符号 - CCHLB1
- CACNB1
- CACNLB1
- MGC41896
- CAB1
UniProt编号 - Q02641
UniProt汇总 FUNCTION: SwissProt: Q02641 # The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting.
SIZE: 598 amino acids; 65714 Da
SUBUNIT: The L-type calcium channel is composed of four subunits: alpha-1, alpha-2, beta and gamma.
SUBCELLULAR LOCATION: Cell membrane, sarcolemma; Peripheral membrane protein; Cytoplasmic side.
TISSUE SPECIFICITY: Expressed in brain, heart and spleen (isoform 1 and 3) and in skeletal muscle (isoform 2).
SIMILARITY: SwissProt: Q02641 ## Belongs to the calcium channel beta subunit family. & Contains 1 SH3 domain.产品使用声明 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Maintain at -20°C in undiluted aliquots for up to 6 months after date of receipt. Avoid repeated freeze/thaw cycles. 包装信息 数量 100 µg
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