• merck millipore,默克密理博,AB1372,Anti-Glutathione-S-Transferase Antibody, S. japonicum form
  • merck millipore,默克密理博,AB1372,Anti-Glutathione-S-Transferase Antibody, S. japonicum form

    产品名称:Anti-Glutathione-S-Transferase Antibody, S. japonicum form
    产品型号:AB1372
    Anti-Glutathione-S-Transferase Antibody, S. japonicum form detects level of Glutathione-S-Transferase & has been published & validated for use in ELISA, IP & WB.

    merck millipore,默克密理博,AB1372,Anti-Glutathione-S-Transferase Antibody, S. japonicum form

  • 产品介绍
  • merck millipore,默克密理博,AB1372,Anti-Glutathione-S-Transferase Antibody, S. japonicum form

    重要规格表

    品种反应性 主要应用 宿主 格式 抗体类型
    Schistosoma japonicum, VrtWB, ELISARbSerumPolyclonal Antibody
    描述
    产品目录编号 AB1372
    品牌系列 Chemicon®
    商名
    • Chemicon
    描述 Anti-Glutathione-S-Transferase Antibody, S. japonicum form
    Alternate Names
    • GST tag
    产品信息
    格式 Serum
    演示 Liquid serum containing sodium azide as a preservative.
    应用
    应用 Anti-Glutathione-S-Transferase Antibody, S. japonicum form detects level of Glutathione-S-Transferase & has been published & validated for use in ELISA, IP & WB.
    主要应用
    • Western Blotting
    • ELISA
    应用说明 Western blot

    Immunoprecipitation

    ELISA

    Optimal working dilutions must be determined by end user.
    生物信息
    免疫原品种 Directed against the full length sequence of GST from schistosoma japonicum, expressed in E. coli.
    表位 S. japonicum form
    宿主 Rabbit
    特异性 GST
    品种反应性 Schistosoma japonicumVertebrates
    抗体类型 Polyclonal Antibody
    Entrez基因编号
    • NM_145740.2
    Entrez基因汇总 Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes function in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding these enzymes are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of some drugs. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class. The alpha class genes, located in a cluster mapped to chromosome 6, are the most abundantly expressed glutathione S-transferases in liver. In addition to metabolizing bilirubin and certain anti-cancer drugs in the liver, the alpha class of these enzymes exhibit glutathione peroxidase activity thereby protecting the cells from reactive oxygen species and the products of peroxidation.
    基因符号
    • GST-epsilon
    • GSTA1
    • GTH1
    • GST2
    • H-A
    • GSTA1-1
    • MGC131939
    UniProt编号
    • P08263
    UniProt汇总 FUNCTION: SwissProt: P08263 # Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.
    SIZE: 222 amino acids; 25631 Da
    SUBUNIT: Homodimer or heterodimer of GSTA1 and GSTA2.
    SUBCELLULAR LOCATION: Cytoplasm.
    TISSUE SPECIFICITY: Liver.
    DOMAIN: SwissProt: P08263 The C-terminal domain may form a component of the hydrophobic substrate-binding site, but in contrast appears not to be directly involved in GSH binding and is not absolutely essential for catalytic activity.
    SIMILARITY: Belongs to the GST superfamily. Alpha family.
    产品使用声明
    使用声明
    • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
    储存和货运信息
    存储条件 Maintain at -70°C for up to 6 months or -20°C for up to 3 months from date of receipt in undiluted aliquots. Avoid repeated freeze/thaw cycles.
    包装信息
    数量 50 µL

    merck millipore,默克密理博,AB1372,Anti-Glutathione-S-Transferase Antibody, S. japonicum form

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