merck millipore,默克密理愽

  • 产品介绍

  • 描述
    产品目录编号 9088-HK
    描述 Ghrelin
    背景信息 These iodinated hormonos are HPLC purified and prepared fresh monthly.
    产品信息
    格式 Iodinated Hormones
    应用
    应用说明 appropriate label hydrating buffer if kit replacement or assay buffer of choice
    生物信息
    Entrez基因编号
    • NM_016362.2
    Entrez基因汇总 Ghrelin is an endogenous ligand for the growth hormone secretagogue receptor (GHSR; MIM 601898) and is involved in regulating growth hormone (GH; MIM 139250) release. Ghrelin is derived from a preprohormone called preproghrelin, which also generates a second peptide called obestatin. Obestatin is an endogenous ligand for the orphan G protein-coupled receptor GPR39 (MIM 602886) and is involved in satiety and decreased food intake.[supplied by OMIM]
    基因符号
    • obestatin
    • GHRL
    • ghrelin
    • MTLRP
    标签 125Iodine
    UniProt编号
    • Q9UBU3
    UniProt汇总 FUNCTION: SwissProt: Q9UBU3 # Obestatin may be the ligand for GPR39. May have an appetite-reducing effect resulting in decreased food intake. May reduce gastric emptying activity and jejunal motility (By similarity).
    SIZE: 117 amino acids; 12911 Da
    SUBCELLULAR LOCATION: Secreted.
    TISSUE SPECIFICITY: Highest level in stomach. All forms are found in serum as well. Other tissues compensate for the loss of ghrelin synthesis in the stomach following gastrectomy.
    PTM: O-octanoylation or O-decanoylation is essential for ghrelin activity. The O-decanoylated forms Ghrelin-27-C10 and Ghrelin-28- C10 differ in the length of the carbon backbone of the carboxylic acid bound to Ser-26. A small fraction of ghrelin, ghrelin-28- C10:1, may be modified with a singly unsaturated carboxylic acid. & Amidation of Leu-98 is essential for obestatin activity (By similarity).
    SIMILARITY: SwissProt: Q9UBU3 ## Belongs to the motilin family.
    理化信息
    放射性 <1.5 μCi
    储存和货运信息
    存储条件 2–8 °C
    包装信息
    数量 125 tubes


上一件merck millipore产品：merck millipore,默克密理博,AB1372,Anti-Glutathione-S-Transferase Antibody, S. japonicum form
下一件merck millipore产品：merck millipore,默克密理博,07-324,Anti-PP2A Antibody, C subunit


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