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品种反应性 主要应用 宿主 格式 抗体类型 H WB Rb Serum Polyclonal Antibody 描述 产品目录编号 AB10320 品牌系列 Chemicon®
商名 - Chemicon
描述 Anti-Cytochrome P450 1B1 Antibody Alternate Names - Cytochrome P450 1B1
背景信息 Cytochrome P450 1B1 (CYP1B1) is active in the metabolism of estrogens to reactive catechols and of different procarcinogens. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and the synthesis of cholesterol, steroids and other lipids. 产品信息 格式 Serum 演示 Raw rabbit serum with 0.05% sodium azide. 应用 应用 Anti-1B1 Antibody detects level of 1B1 & has been published & validated for use in WB. 主要应用 - Western Blotting
应用说明 Suggested dilutions:
Western Blot: 1:5000生物信息 免疫原品种 Recombinant human 1B1 宿主 Rabbit 品种反应性 Human 抗体类型 Polyclonal Antibody Entrez基因编号 - NM_ 000104
Entrez基因汇总 This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The enzyme encoded by this gene localizes to the endoplasmic reticulum and metabolizes procarcinogens such as polycyclic aromatic hydrocarbons and 17beta-estradiol. Mutations in this gene have been associated with primary congenital glaucoma; therefore it is thought that the enzyme also metabolizes a signaling molecule involved in eye development, possibly a steroid. 基因符号 - GLC3A
- CP1B
- CYPIB1
- EC 1.14.14.1
UniProt编号 - Q16678
UniProt汇总 FUNCTION: SwissProt: Q16678 # Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.
SIZE: 543 amino acids; 60846 Da
SUBCELLULAR LOCATION: Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
SIMILARITY: SwissProt:Q16678 # Belongs to the cytochrome P450 family.产品使用声明 质量保证 Routinely evaluated by immunoblot. 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Maintain at -20°C for up to 12 months from date of receipt. 包装信息 数量 50 µL
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