merck millipore,默克密理博,14-680M,HIPK3 Protein, active, 250 µg

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Merck Millipore 默克密理愽

描述
产品目录编号	14-680M
品牌系列	Upstate
商名	Upstate
描述	HIPK3 Protein, active, 250 µg
概述	N-terminal 6His-tagged, recombinant, human HIPK3, amino acids 161-562

应用
应用	Active, N-terminal 6His-tagged, recombinant, human HIPK3, amino acids 161-562, for use in Kinase Assays.
主要应用	Kinase Assay

生物信息
来源	expressed by baculovirus in Sf21 cells
品种	Human
Entrez基因编号	NM_005734.3 NM_001048200.1
基因符号	FIST3 HIPK3 FIST DYRK6 ANPK PKY YAK1
蛋白靶	HIPK3
纯化方法	Ni²⁺/NTA-agarose
靶子系列	CMGC
UniProt编号	Q9H422
UniProt汇总	FUNCTION: SwissProt: Q9H422 # Seems to negatively regulate apoptosis by promoting FADD phosphorylation. Enhances androgen receptor-mediated transcription. May act as a transcriptional corepressor for NK homeodomain transcription factors. SIZE: 1215 amino acids; 133743 Da SUBUNIT: Interacts with Nkx1-2. Interacts with FAS and DAXX. Probably part of a complex consisting of HIPK3, FAS and FADD. Interacts with and stabilizes ligand-bound androgen receptor (AR) (By similarity). Interacts with UBL1/SUMO-1. SUBCELLULAR LOCATION: Cytoplasm. Nucleus. TISSUE SPECIFICITY: Overexpressed in multidrug resistant cells. Highly expressed in heart and skeletal muscle, and at lower levels in placenta, pancreas, brain, spleen, prostate, thymus, testis, small intestine, colon and leukocytes. Not found in liver and lung. PTM: Autophosphorylated, but autophosphorylation is not required for catalytic activity (By similarity). & May be sumoylated (By similarity). SIMILARITY: SwissProt: Q9H422 ## Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. HIPK subfamily. & Contains 1 protein kinase domain.

产品使用声明
质量保证	Routinely evaluated by phosphorylation of MBP (Catalog # 13-104)
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Stable 6 months at -70°C from date of shipment

包装信息
数量	250 µg
包装	Also available in 10 μg size (cat#14-680) and in bulk (cat#14-680-K).

merck millipore,默克密理博,14-680M,HIPK3 Protein, active, 250 µg

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