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品种反应性 主要应用 宿主 格式 抗体类型 R WB Rb Affinity Purified Polyclonal Antibody 描述 产品目录编号 AB10141 品牌系列 Chemicon®
商名 - Chemicon
描述 Anti-Aquaporin 9 Antibody Alternate Names - AQP-9
背景信息 Water is a critical component of all living cells. Interestingly, tissue membranes show a great degree of water permeability. Mammalian red cells, renal proximal tubules, and descending thin limb of Henle are extraordinarily permeable to water. Water crosses hydrophobic plasma membranes either by simple diffusion or through a facilitative transport mechanism mediated by special protein "aquaporin". A new member of AQP family, Aquaporin-9 (AQP9), has been cloned from human leukocytes by homology cloning (Ishibashi et al. 1997). It is mostly homologous with AQP3 and AQP7 (54-48% identity). AQP9 (295 AA) is primarily expressed in peripheral leukocytes, and lesser amounts in liver, lung and spleen. AQP9 is permeable to water and urea. Unlike AQP3 and AQP7, it did not facilitate glycerol transport. AQP families of proteins are predicted to contain six transmembrane domains. The N and C-terminus are predicted to be cytoplasmic. 产品信息 格式 Affinity Purified 控制 - Liver lysate
演示 Purified in 0.1M Tris-Glycine (pH7.4) 15mM NaCl. 应用 应用 Anti-Aquaporin 9 Antibody detects level of Aquaporin 9 & has been published & validated for use in WB. 主要应用 - Western Blotting
应用说明 Western Blot: 0.5 µg/mL 生物信息 免疫原品种 Synthetic Linear Peptide. 表位 C-Terminus 宿主 Rabbit 特异性 Recognizes rat AQP9 品种反应性 Rat 抗体类型 Polyclonal Antibody Entrez基因编号 - NP_075249
Entrez基因汇总 solute channel involved in passage of carbamides, polyols, purines, and pyrimidines [RGD] 基因符号 - Aqp9
UniProt编号 - P56627
UniProt汇总 FUNCTION: Forms a channel with a broad specificity. Mediates passage of a wide variety of non-charged solutes including carbamides, polyols, purines, and pyrimidines in a phloretin- and mercury-sensitive manner, whereas amino acids, cyclic sugars, Na(+), K(+), Cl(-), and deprotonated monocarboxylates are excluded. Also permeable to urea but not to glycerol.
SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein.
DOMAIN: Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).
SIMILARITY: Belongs to the MIP/aquaporin (TC 1.A.8) family产品使用声明 质量保证 Routinely evaluated by immunoblot. 使用声明 - Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
储存和货运信息 存储条件 Maintain at 2-8°C for up to 12 months from date of receipt. 包装信息 数量 100 µg
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下一件merck millipore产品：merck millipore,默克密理博,SCNY00060,Steriflip-NY，60 µm，尼龙网格，射线灭菌
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