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merck millipore,默克密理博,540215,PTP CD45 Inhibitor - CAS 345630-40-2 - Calbiochem
产品名称：PTP CD45 Inhibitor - CAS 345630-40-2 - Calbiochem
产品型号：540215
The PTP CD45 Inhibitor, also referenced under CAS 345630-40-2, controls the biological activity of PTP CD45. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation app More>>
merck millipore,默克密理博,540215,PTP CD45 Inhibitor - CAS 345630-40-2 - Calbiochem
- 产品介绍
重要规格表
经验配方 CAS号 C₁₉H₁₇NO₃ 345630-40-2 描述 概述 A cell-permeable, potent, selective, competitive, and reversible inhibitor of CD45 (IC50 = 200 nM or 3.8 µM using pNPP or phosphorylated Ick505 peptide as a substrate, respectively). Does not effectively inhibit PTPIB (IC50 >30 µM using phosphorylated Ick505 peptide as a substrate). The phenanthrenedione group does not function as a thiol oxidizing agent. One of the most potent inhibitor of phosphatase tensin homolog deleted on chromosome 10 (PTEN) that enhances PIP3 signaling in a variety of cells and improves the efficacy of granulocyte transfusion in murine models of neutropenia-related pneumonia. 产品目录编号 540215 品牌系列 Calbiochem®
同义词 N-(9,10-Dioxo-9,10-dihydro-phenanthren-2-yl)-2,2-dimethyl-propionamide, PTPase CD45 Inhibitor, Protein Tyrosine Phosphatase CD45 Inhibitor, PTEN Inhibitor V, SF1670, PTP Inhibitor XIX, PTP1B Inhibitor VI, PTPN2/TCPTP Inhibitor, SHP1 Inhibitor VII, YPTP1 Inhibitor, YOP Inhibitor 参考 参考 Li, Y., et al. 2011. Blood 117, 6702.
Urbanek, R.A., et al. 2001. J. Med. Chem. 44, 1777.产品信息 CAS号 345630-40-2 具有ATP竞争性 N 形式 Red-violet solid Hill配方 C₁₉H₁₇NO₃ 化学配方 C₁₉H₁₇NO₃ Molar Mass 307.3 可逆 Y 结构配方图像 生物信息 主靶 CD45 using pNPP as a substrate 主靶IC50 200 nM or 3.8 µM against CD45 using pNPP or phosphorylated Ick505 peptide as a substrate, respectively 纯度 ≥ 97% by HPLC 理化信息 细胞可渗透 Y 溶解度 DMSO or EtOH 储存和货运信息 货运代码 Blue Ice Only
毒性 Harmful
储存 +2°C to +8°C
避光 Protect from light
无需冷冻 No
特殊指南 Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C. 包装信息 惰性气体下包装 Packaged under inert gas
上一件merck millipore产品：merck millipore,默克密理博,422709,KN-92 - CAS 1135280-28-2 - Calbiochem
下一件merck millipore产品：merck millipore,默克密理博,ABS31,Anti-2A Peptide Antibody
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