merck millipore,默克密理博,MABC773,Anti-SHP-1, clone EPR5519, Rabbit Monoclonal Antibody

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merck millipore,默克密理博,MABC773,Anti-SHP-1, clone EPR5519, Rabbit Monoclonal Antibody
产品名称：Anti-SHP-1, clone EPR5519, Rabbit Monoclonal Antibody
产品型号：MABC773
This Anti-SHP-1, clone EPR5519, Rabbit Monoclonal Antibody is validated for use in Western Blotting and Immunohistochemistry for the detection of SHP-1.

merck millipore,默克密理博,MABC773,Anti-SHP-1, clone EPR5519, Rabbit Monoclonal Antibody

产品介绍

merck millipore,默克密理博,MABC773,Anti-SHP-1, clone EPR5519, Rabbit Monoclonal Antibody

重要规格表

品种反应性	主要应用	宿主	格式	抗体类型
H	IHC, WB	Rb	Unpurified	Monoclonal Antibody

描述
产品目录编号	MABC773
描述	Anti-SHP-1, clone EPR5519, Rabbit Monoclonal Antibody
Alternate Names	SH-PTP1 Tyrosine-protein phosphatase non-receptor type 6 Hematopoietic cell protein-tyrosine phosphatase Protein-tyrosine phosphatase 1C PTP-1C Protein-tyrosine phosphatase SHP-1
背景信息	Src Homology region 2 domain Phosphatase 1 (SHP-1) is also known as Protein Tyrosine Phosphatase 1C (PTP1C), Protein Tyrosine Phosphatase non-receptor type 6 (PTPN6), and Hematopoietic Cell Phosphatase (HCPH). SHP-1 is a SH2 domain-containing cytosolic tyrosine phosphatase characterized by a catalytic phosphatase domain of approximately 240 amino acids that selectively dephosphorylates tyrosine residues in proteins; the SH2 domains are critical for SHP-1 to bind to ITIM domains in inhibitory immunoreceptors. SHP-1 is highly expressed in hematopoietic tissues and has a negative impact on lymphocyte signaling. SHP-1 is implicated in the control of tyrosine kinase signaling pathways in cellular proliferation, with a potential role in cancer.

产品信息
格式	Unpurified
演示	Rabbit monoclonal in buffer containing PBS with up to 0.1% sodium azide, 0.05% BSA, and 50% glycerol.

应用
应用	This Anti-SHP-1, clone EPR5519, Rabbit Monoclonal Antibody is validated for use in Western Blotting and Immunohistochemistry for the detection of SHP-1.
主要应用	Immunohistochemistry Western Blotting
应用说明	Immunohistochemistry Analysis: A 1:1,000-2,000 dilution from a representative lot detected SHP-1 in human tonsil tissue. Produced in collaboration with Epitomics™

生物信息
免疫原品种	Synthetic peptide corresponding to the N-terminus of human SHP-1.
表位	N-terminus
克隆	EPR5519
浓缩	Please refer to lot specific datasheet.
宿主	Rabbit
同种型	IgG
品种反应性	Human
Species Reactivity Note	Human
抗体类型	Monoclonal Antibody
基因符号	PTP1C PTPN6 HCP
纯化方法	Unpurified
UniProt编号	P29350

产品使用声明
质量保证	Evaluated by Western Blotting in Jurkat, Raji, and human lymph node lysates. Western Blotting Analysis: A 1:1,000-10,000 dilution of this antibody detected SHP-1 in Jurkat, Raji, and human lymph node lysates.
使用声明	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

储存和货运信息
存储条件	Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.

储存和货运信息

存储条件

Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.
Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.